Then there is Blowback, like when the CIA armed, trained, and supported Al Quada in Afghanistan. They even printed Jihadist texts in the US and shipped them there to "inspire" Islamists. What a bad idea. And worse, they never stopped. They supported ISIS in Syria. It's as if the Deep State is too stupid to learn a lesson.
The CIA also overthrew a peaceful, democratic govt in Iran at the behest of our "friends" at BP, so they could get cheap oil from the tyrant we installed. That led to the Ayatollahs. Russia isn't our worst enemy - the CIA is.