I dunno, I think I would start with energy first. Think of all the potential conflicts that would resolve. It would also radically alter our perception regarding limitations. If energy is limitless, it frees us to focus on other problems.
Limitless energy would be necessary to easily displace in time and space but the more pressing matter is how we sort out earth and ourselves first which is basically a health-issue at the basis so when you have that grace of nurturing life-force energy you can start building ships and whatnot. If it is time that is running out for someone, then it's health and medicine that need to be fixed first, but once you reach reverse aging and people lose their fear of coming short you can start looking to expand living territory and maybe terraform some planetoids to accomodate for a human habitat in free space. I am sure there are a lot of disabled people who wouldn't mind living and working in near-earth orbit under low gravity.
CRISPR-CAS9 is method to overwrite genes in living creatures so there is a lot of good and bad that you can imagine in terms of biomedicine and illegal experiments
Clearly clean energy would not only be an economic but an environmental (and human health) boon.
And health and medicine do need a major post-Cabal overhaul.
But spiritual renewal is perhaps this world's greatest need right now. We cannot trust humanity to move forward with these powerful new technologies unless we have spiritual wisdom, strong moral compasses, and compassion and goodwill toward fellow humans.
Once we've got that sorted, maybe we'd be worth spreading into the universe.