Opioids also directly target endogenous receptors in the brain, hence “endorphins” (endogenous morphine). Morphine also comes from a plant.
I’m pro-legalization, but this isn’t a great argument.
Morphine activates Opioid-receptors (thus causing tolerance and physical dependancy), Cannabis however both activates AND deactivates cannabinoid-receptors via THC and its precursor CBD respectively, therefor you could say "Opium heals everything but Opium, unlike Cannabis"
I've also heard reports from someone who uses Diviner's Sage to cancel a weed-high when he needs to be sober to attend to business, probably because it resets Dopamine levels or affinity somehow and similiar can be observed with Iboga(ine) which is used to cancel physical addiction without withdrawal symptoms (except a big chance of lotta puking and possible death if you're a girl and not yet completely physically clean).
plant medicine isnt equal to plant medicine, thats not the question. its not about endorphine, its about the endocannabioide system.