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the winds of change
An event or series of events that signals or precipitates large and important changes.
A meeting between delegates for the two warring countries is leading some to speculate that the winds of change may be blowing through the region.
It seems the winds of change are about to sweep through the pharmaceutical industry, as new laws seek to dismantle their long-despised ability to raise prices for life-saving drugs at their own discretion.
John F Kennedy signed the gold standard agreement eight days before he was assassinated.