On this day…

April 18, 1906

The Great San Francisco Earthquake topples buildings,killing thousands

2014

Mt. Everest sees its singledeadliest day

2012

Dick Clark, host of “American Bandstand” and “New Year’s Rockin’ Eve,”dies

1983

Suicide bomberdestroys U.S. embassy in Beirut

1521

Martin Luther defiant at Diet of Worms

1945

War correspondent Ernie Pylekilled

1942

Doolittle leads air raid on Tokyo

1983

Joan Benoit wins Boston Marathon

1958

Federal court decides to release poet Ezra Pound from hospital for criminally insane

1956

Grace Kelly and Prince Rainier of Monaco marry

1989

Chinese students protest against government

1775

Revere and Dawes warn of Britishattack

https://www.history.com/this-day-in-history

>>13453565

Walker Warnock – WW

Q posts 477 455 (possibly 4 as well?

>>13453650

The [D]evil is in the [D]etails

Battlefield Medicine

Dr. Tristan McClure-Begley

The Battlefield Medicine programsupports military readiness in far-forward deployed settings by overcoming logistical obstacles to manufacturing and delivery of urgently needed pharmaceutical products used to treat emerging threats.

Battlefield logistics are a challenge regardless of the mission. Adversaries, terrain, and the environment all serve to complicate the process of delivering supplies to warfighters. The current Department of Defense (DoD) approach to medical supply logistics is limited in its reach to far-forward emergency settings, response to emergent in-theater threats, and utility for bio-preparedness stockpiling. It can often take weeks to months to manufacture and airlift organic pharmaceuticals and protein therapeutics to battlefield frontlines, meaning that critical medical supplies often do not arrive in time where they are needed most. Furthermore, the need to prepare medical supplies in advance based on an anticipated, specific threat can result in wasted materials, labor, and money when that threat is not realized. The DoD needs a new approach.

Battlefield Medicine seeks to address this capability gap through two integrated research thrusts: the Pharmacy on Demand (PoD) and Biologically-derived Medicines on Demand (Bio-MOD) initiatives. The combined efforts seek to develop miniaturized device platforms and techniques that can produce multiple small-molecule active pharmaceutical ingredients (APIs) and therapeutic proteins in response to specific battlefield threats and medical needs as they arise. PoD research is aimed at developing and demonstrating the capability to manufacture multiple APIs of varying chemical complexity using shelf-stable precursors, while Bio-MOD research is focused on developing novel, flexible methodologies for genetic engineering and modification of microbial strains, mammalian cell lines, and cell-free systems to synthesize multiple protein-based therapeutics. As a proof of concept, both PoD and Bio-MOD efforts will seek to develop platforms for manufacturing single-dose levels of FDA-approved APIs and biologics and demonstrate high purity, efficacy, and potency in short timeframes.

In developing a flexible, miniaturized synthesis and manufacturing platform, Battlefield Medicine will leverage continuous flow approaches that will, if successful, pave the path forward for enabling distributed, on-demand medicine manufacturing capabilities in battlefield and other austere environments. Additionally, the platform would have built-in flexibility to produce multiple types of therapeutics through its modular reaction design. The ultimate vision for Battlefield Medicine is to enable effective small-batch pharmaceutical production that obviates the need for individual drug stockpiling, cold storage, and complex logistics.

https://www.darpa.mil/program/battlefield-medicine

DARPA Awards Moderna Therapeutics a Grant for up to $25 Million to Develop Messenger RNA Therapeutics™

October 2, 2013 at 9:00 AM EDT

PDF Version

Research to focus on antibody production for immune defense

https://investors.modernatx.com/news-releases/news-release-details/darpa-awards-moderna-therapeutics-grant-25-million-develop

Remembering the lives lost to COVID-19: Terrence James, 49, of Galveston, Texas

Terrence James, 49, of Galveston, Texas, died on Feb. 19, 2021, after becoming ill with COVID-19. He is among the more than 565,000 Americans who have succumbed to the disease since the first known fatality in the United States in early 2020.

His wife, Ebony James, told Yahoo News that her husband was a man of faith who loved God and his family fearlessly and that he was also passionate about helping people.

“If someone were to tell him about an issue or concern that they had, he would always listen. He never missed an opportunity to say, ‘OK, let's pray for it right now,” Ebony said, adding that her husband “always made an effort to let people know that he cared.”

Terrence James was a sixth grade social studies teacher at Central Middle School in Galveston. He also managed a nonprofit organization called Leaders of Tomorrow, which gave at-risk youth the chance to experience travel. “He took them places where they ordinarily wouldn't get an opportunity to go,” Ebony said.

At home, Terrence was a devoted husband and father. The couple, who had been together for 12 years, had just celebrated their 10th wedding anniversary in December. Ebony said her husband was her best friend.

Both Ebony and Terrence contracted COVID-19 in late January and were hospitalized. Ebony recuperated and was sent home, but her husband’s health continued to decline. After spending 23 days in the hospital, he died from COVID-19 complications.

Losing Terrence has been devastating for his wife and children. During her grieving process, Ebony said what gives her comfort is knowing she cherished every moment with her husband when he was alive.

“It's a beauty to be able to not have to look back and say, ‘I wish I would have. I wish I could have.’ I don't have that,” Ebony said. “I just have the beauty of our relationship, and I would most certainly say being married to a larger-than-life person who could love me, and love my children, and treat us so wonderfully is something that I'll cherish for the rest of my life.”

https://www.yahoo.com/news/remembering-the-lives-lost-to-covid-19-terrence-james-49-of-galveston-texas-104322211.html

Neighbor who tossed an elderly Jewish woman off a balcony while yelling 'Allahu Akbar' avoids trial because he smoked weed

France's top court ruled on Wednesday that the killer of an elderly Jewish woman will not go on trial, France24 reported.

Kobili Traoré admitted to murdering his neighbor, Sarah Halimi, in 2017. He shouted "Allahu Akbar," or "God is great" in Arabic, and "I killed the devil," shortly before throwing her off the balcony of her third-floor Paris apartment, The New York Times said.

On Wednesday, the Court of Cassation - France's final court of appeal - affirmed two prior judgments that ruled that Traoré could not be held criminally responsible for his actions because he was in a state of drug-induced psychosis.

Traoré, a drug dealer, smoked pot every day for 13 years and had up to 15 joints a day, Israel Hayom reported. Toxicological analysis revealed the presence of cannabis in his blood on the day he was arrested, the French newspaper Libération said.

The court noted that "a person is not criminally responsible if suffering, at the time of the event, from psychic or neuropsychic disturbance that has eliminated all discernment or control," The Times said.

Whether the disturbance was brought on through voluntary drug use is not a legally important distinction, the court said.

In December 2019, President Emmanuel Macron made a rare intervention by criticizing the Paris appeals court for saying that Traore was unfit for trial.

"Even if, in the end, the judge decided that there was no criminal responsibility, there is a need for a trial," Macron said in 2020.

The country's top magistrates then criticized Macron for impacting the "independence of the justice system," The Times of Israel reported.

The ruling has angered French politicians and France's Jewish community, the largest in Europe.

Dozens of French senators have reacted by proposing a revision to the law that exonerates a crime due to a drug-induced psychosis, The New York Times said.

https://www.yahoo.com/news/neighbor-tossed-elderly-jewish-woman-121046808.html

>>13454056

On the Anniversary of the San Fran Quake.

On this day >>13453546

>>13454104

>>13454195

Weren't there some videos a few years back, where China had tanks chilling in Mexico?

Can't find them now.