Anonymous ID: 981a4a Feb. 24, 2020, 1:10 a.m. No.8232800   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>2818 >>2907

>>8232695

https://www.lifeextension.com/magazine/2014/1/turn-off-the-cytokine-switch

Summary

Chronic inflammation accelerates aging, producing symptoms that we recognize as diseases that cause early death. Scientists have now discovered the accelerator switch, in the form of HMGB1, the molecule that triggers the release of inflammatory cytokines under a wide variety of circumstances.

 

Anti-HMGB1 therapies, therefore, are avidly sought-after by big pharma companies. While producing dramatic results in the laboratory, however, no anti-HMGB1 drug is anywhere near market-ready because treatments to date use large antibody molecules that canโ€™t be given orally and that have unacceptable side effects.

 

But mung beans and green tea, in use for thousands of years in traditional Chinese medicine, contain safe, powerful HMGB1-fighting substances. Extract of mung bean seed coat and EGCG from green tea leaf extract can be given orally, and in preclinical studies have proven to be highly effective at shutting down HMGB1-induced inflammation in a life-saving fashion.

But mung beans and green tea, in use for thousands of years in traditional Chinese medicine, contain safe, powerful HMGB1-fighting substances.

Anonymous ID: 981a4a Feb. 24, 2020, 1:13 a.m. No.8232818   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>2907

>>8232800

It is also a useful model for understanding the role of anti-HMGB1 therapies in the most extreme example of out-of-control inflammation. In sepsis, massive amounts of HMGB1 trigger an outpouring of cytokines. It is this resulting inflammation, and not the infecting germ, that ultimately kills the patient.65,66 And once those cytokines are on the loose, itโ€™s typically too late to fight back with anti-cytokine therapies.

massive amounts of HMGB1 trigger an outpouring of cytokines. It is this resulting inflammation, and not the infecting germ, that ultimately kills the patient.

Anonymous ID: 981a4a Feb. 24, 2020, 1:20 a.m. No.8232864   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun

>>8232851

As Calianon this hits close to home. I blame Pelosi though. Still, these are homeless Americans, not your average Indian citizen. I understand what you're trying to convey, but I could easily one up you with their holy river.

Anonymous ID: 981a4a Feb. 24, 2020, 1:44 a.m. No.8233005   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>3016 >>3019 >>3028 >>3115

Calianon here, probably nothing, i'm sure it's paranoia, there was an article about Positive Coronavirus patients about 2-3 hours away from me not being able to be moved to their intended destination, so they've just been sitting. I've had a strange cough past few weeks. When I lay down, i'm horribly congested and there's alot of phlegm ect, i'm mostly okay, don't feel sick persay, but there is a nagging tickle in the back of my throat. I smoke a bowl of weed about every hour or so, and I smoke cigarettes, still, I haven't had a persistent cough like this in awhile. Terrible diet, no vitamins ect, am I fuked?