Gain of Function research role in COVID-19

They knew animal virus transmission to humans was only possible if the lab altered the virus. Zoological diseases don’t hold much threat of transmitting to humans. Gain-of-function research involves experimentation that aims or is expected to (or actually does) increase the transmissibility and/or virulence of pathogens. Such research aims to improve understanding of disease causing agents, their interaction with human hosts, and their potential to cause pandemic, but can also pose risks regarding biosecurity and biosafety.

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https://www.researchgate.net/profile/Domina-Petric/publication/343627980_The_role_of_dual-use_gain-of-function_research_in_SARS-CoV-2_origin/links/5f34f555458515b7291bf5cf/The-role-of-dual-use-gain-of-function-research-in-SARS-CoV-2-origin.pdf?origin=publication_detail

Chinese and US scientists, Shi Zhengli and Peter Daszak, including Ralph S. Baric (USA; University of North Carolina), once again with funding from US and Chinese Governments, used COVID-19 Spike protein to artificially create a coronavirus that scientists call “a chimeric virus”, essentially a clone - one that is manufactured in a laboratory. Scientific literature is replete with several research papers on the creation of chimeric viruses in the pursuit of discovering and creating deadlier viruses than those that exist in nature. Such research is referred as Gain of Function (GoF) research and is meant to create more virulence in order to be prepared with a cure (therapeutic or vaccine) in the event that such a virus appears or is released by an enemy agent or state..

https://ppf.org.in/opinion/sars-cov2-is-a-chimera-with-hiv-gene-manipulation