Anonymous ID: 2af314 Aug. 22, 2020, 9:45 p.m. No.10389250   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>9281

>>10389175

Okie dokie, sweetie.

 

https://www.nature.com/articles/s41421-020-0156-0

 

Both CQ and HCQ are weak bases that are known to elevate the pH of acidic intracellular organelles, such as endosomes/lysosomes, essential for membrane fusion5. In addition, CQ could inhibit SARS-CoV entry through changing the glycosylation of ACE2 receptor and spike protein6. Time-of-addition experiment confirmed that HCQ effectively inhibited the entry step, as well as the post-entry stages of SARS-CoV-2, which was also found upon CQ treatment (Supplementary Fig. S2). To further explore the detailed mechanism of action of CQ and HCQ in inhibiting virus entry, co-localization of virions with early endosomes (EEs) or endolysosomes (ELs) was analyzed by immunofluorescence analysis (IFA) and confocal microscopy. Quantification analysis showed that, at 90โ€‰min p.i. in untreated cells, 16.2% of internalized virions (anti-NP, red) were observed in early endosome antigen 1 (EEA1)-positive EEs (green), while more virions (34.3%) were transported into the late endosomalโ€“lysosomal protein LAMP1+ ELs (green) (nโ€‰>โ€‰30 cells for each group). By contrast, in the presence of CQ or HCQ, significantly more virions (35.3% for CQ and 29.2% for HCQ; Pโ€‰<โ€‰0.001) were detected in the EEs, while only very few virions (2.4% for CQ and 0.03% for HCQ; Pโ€‰<โ€‰0.001) were found to be co-localized with LAMP1+ ELs (nโ€‰>โ€‰30 cells) (Fig. 1b, c).

 

Translation:

Shit makes a COVID infection difficult because it creates a "Barrier" against infection.

Anonymous ID: 2af314 Aug. 22, 2020, 10:15 p.m. No.10389438   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>9464

>>10389365

>>10389373

Posts drop off into the archives. Since migration to 8kun, archives no longer workey.

 

Q !CbboFOtcZs ID: 8704f4 No.1991829 ๐Ÿ“

Jul 1 2018 20:13:38 (EST)

There will be no civil war.

Coordinated MSM hysteria designed to instill fear - change narrative.

NK is NOT advancing their weapons program.

Coordinated MSM hysteria designed to instill fear - change narrative.

FAKE NEWS!

Q

 

https://qanon.pub/#1664