Can Zn Be a Critical Element in COVID-19 Treatment?

https://link.springer.com/article/10.1007/s12011-020-02194-9

Abstract

The current COVID-19 pandemic caused by SARS-CoV-2 has prompted investigators worldwide to search for an effective anti-viral treatment. A number of anti-viral drugs such as ribavirin, remdesivir, lopinavir/ritonavir, antibiotics such as azithromycin and doxycycline, and anti-parasite such as ivermectin have been recommended for COVID-19 treatment. In addition, sufficient pre-clinical rationale and evidence have been presented to use chloroquine for the treatment of COVID-19. Furthermore, Zn has the ability to enhance innate and adaptive immunity in the course of a viral infection. Besides, Zn supplement can favour COVID-19 treatment using those suggested and/or recommended drugs. Again, the effectiveness of Zn can be enhanced by using chloroquine as an ionophore while Zn inside the infected cell can stop SARS-CoV-2 replication. Given those benefits, this perspective paper describes how and why Zn could be given due consideration as a complement to the prescribed treatment of COVID-19.

Full article attached as PDF

>>10395867

Marilyn Monroe from 1947

>>10395878

Alice Denham in a bullet bra

She was a Playboy Playmate in 1956

The robot in Fritz Lang’s 1927 silent film, Metropolis

>>10396016

Metrópolis (1927) | Full Movie

restored and with English titles and text

This was made in the Weimar Republic of Germany

A few years before the events portrayed in the TV series

Babylon, Berlinwhich I recommend that you watch as well.

>>10396064

The novel version of the classic silent sci-fi movie Metropolis by Fritz Lang. Students of the film know that it was severely cut and edited after its first release, and further cut during its US release. There have been several attempts to restore the film over the decades, but it has never been brought back to its original version. This novel has several scenes that are not in any video version currently available. It may be that they were never filmed or they are just forever lost. This book gives a glimpse of what may or might have been.

https://ia800406.us.archive.org/22/items/TheaVonHarbou19271963Mertopolis/Thea%20Von%20Harbou%20%281927-1963%29%20Mertopolis.pdf

The above PDF has 228 pages

>>10396107

>>10396126

Zinc and respiratory tract infections: Perspectives for COVID‑19 (Review)

https://www.spandidos-publications.com/10.3892/ijmm.2020.4575

Abstract

In view of the emerging COVID‑19 pandemic caused by SARS‑CoV‑2 virus, the search for potential protective and therapeutic antiviral strategies is of particular and urgent interest. Zinc is known to modulate antiviral and antibacterial immunity and regulate inflammatory response. Despite the lack of clinical data, certain indications suggest that modulation of zinc status may be beneficial in COVID‑19. In vitro experiments demonstrate that Zn2+ possesses antiviral activity through inhibition of SARS‑CoV RNA polymerase. This effect may underlie therapeutic efficiency of chloroquine known to act as zinc ionophore. Indirect evidence also indicates that Zn2+ may decrease the activity of angiotensin‑converting enzyme 2 (ACE2), known to be the receptor for SARS‑CoV‑2. Improved antiviral immunity by zinc may also occur through up‑regulation of interferon α production and increasing its antiviral activity. Zinc possesses anti‑inflammatory activity by inhibiting NF‑κB signaling and modulation of regulatory T‑cell functions that may limit the cytokine storm in COVID‑19. Improved Zn status may also reduce the risk of bacterial co‑infection by improving mucociliary clearance and barrier function of the respiratory epithelium, as well as direct antibacterial effects against S. pneumoniae. Zinc status is also tightly associated with risk factors for severe COVID‑19 including ageing, immune deficiency, obesity, diabetes, and atherosclerosis, since these are known risk groups for zinc deficiency. Therefore, Zn may possess protective effect as preventive and adjuvant therapy of COVID‑19 through reducing inflammation, improvement of mucociliary clearance, prevention of ventilator‑induced lung injury, modulation of antiviral and antibacterial immunity. However, further clinical and experimental studies are required.

Full article attached as PDF

That's All There is There Ain't No More

>>10396236

Flatten the curve, honey child

[Take 'Em to the Door] That's All There is There Ain't No More Blues

1925 was a damn fine year.

Centenary is coming soon!

I wonder what the MSM

Is going to make of a treatment

That a reporter pointed out, has been around for 100 years

And which has a 35% rate of effectiveness?

I think that whatever they do

They are damned!

Do they like the FDA actions?

Damned if they do, damned if they don't.

100 years ago

The President was in the midst of a battle

With the Senate Foreign Relations Committee

Who wanted to return the Shandong peninsula

To china!

Woodrow Wilson wanted it to remain

In the hands of Japan

This Chinese issue would become a key election issue

Later that fall, Republican Warren Harding

Would win the Presidency