Facing extermination, the Arawaks organized and attempted to fight back against the Spaniards. But they were little match against the armor, muskets, swords and horses of the Europeans. The Spaniards hung or burned Indians that they took captive. By this point, the Arawaks began committing mass suicides. They fed cassava poison to their infants to save them from the Spanish. In two years, half of the 250,000 Indians on Haiti were dead, either through murder, mutilation or suicide. By 1550, there were 500 Indians. By 1650, the Arawaks had been wiped out from the island.
https://rapidcityjournal.com/lifestyles/people/top-5-atrocities-committed-by-christopher-columbus/collection_76ebb2b8-f63d-11e3-a137-001a4bcf887a.html#5