pb discussed in lb
▶Anonymous (You) 11/13/20 (Fri) 09:18:23bfb0f9 (14) No.11625564 >>11625597 >>11625613
>>11625289
>What if I told you that ct cut-off values are irrelevant?
>What if I told you that you can never have too many PCR amplification cycles?
Explanation:
“PCR detection of viruses is helpful so long as its accuracy can be understood: it offers the capacity to detect RNA in minute quantities, but whether that RNA represents infectious virus may not be clear.”
"A PCR test might find the virus it was looking for. This results in a PCR positive, but a crucial question remains: is this virus active, i.e. infectious, or virulent? The PCR alone cannot answer this question."
https://www.cebm.net/covid-19/pcr-positives-what-do-they-mean/
https://www.publichealthontario.ca/-/media/documents/ncov/main/2020/09/cycle-threshold-values-sars-cov2-pcr.pdf?la=en
This document provides an overview of Ct values with a focus on how they are determined, their relationship to viral load, and how Ct values may contribute to the interpretation of positive rRT-PCR
results among patients with low pretest probability.