Anonymous ID: 5c7243 Jan. 18, 2021, 8:32 p.m. No.12597782   🗄️.is 🔗kun   >>7851

>>12597730

>diacetyl

Diacetyl has been shown to alter the amino acid arginine which could interfere with protein structure and function. Additionally diacetyl can bind to DNA and form guanosine adducts which can cause DNA uncoiling and cell death. In vitro studies on human cells also suggest that diacetyl alters the structure and function of the extracellular matrix and modifies epithelial cell responses to growth factors.[15] Human cells exposed to diacetyl also increase secretion of substance P which causes mucus hypersecretion, airway smooth muscle contraction, and edema.[16] Studies in rats have demonstrated significant airway epithelial damage and necrosis after exposure to diacetyl