Could Type 1 Diabetes Be Reversible After All?
Type 1 diabetes is characterized by the loss of insulin-producing 𝛽 cells in the pancreas and has largely been thought to be irreversible—until now.
Newly published research suggests that there might be a cure for type 1 diabetes after all.
FMD restores insulin-dependent glucose control
FMD improves the cytokine profile
FMD triggers the regeneration of pancreatic beta cells
https://chriskresser.com/could-type-1-diabetes-be-reversible-after-all/
Type 1 diabetes: Vitamin D deficiency occurs in early stage
Immunomodulatory Effect of Vitamin D
1,25(OH)2D3 plays an immunomodulatory role in the prevention of T1DM, through the vitamin D receptor (VDR) expressed in antigen presenting cells, activated T cells [9], and pancreatic islet β-cells [10]; this has been demonstrated in many trials done on nonobese diabetic mice (NOD)—a murine model of human IDDM, spontaneously developing diabetes mellitus (DM)—using 1,25(OH)2D3 or its analogue (1,25(OH)2D3, MC1288 (20-epi-1,25(OH)2D3), or KH1060 (1,25(OH)2-20-epi-22-oxa-24,26,27,-trishomovitamin D) [9]. Conversely, 1,25(OH)2D3-deficient mice were at higher risk of developing DM, with a more aggressive course when deficiency is present early in life [11, 12]. 1,25(OH)2D3, administered early on, protects against or reduces the severity of pancreatic insulitis via a dual action, on the pancreatic beta cells and on the immune cells [13]. Furthermore, administration of 1,25(OH)2D3 in combination with cyclosporine A, after the onset of the autoimmune attack, which is known as a prediabetic state, can prevent clinical diabetes
https://www.hindawi.com/journals/ije/2013/148673/
https://www.sciencedaily.com/releases/2014/02/140227115426.htm