Genetic modification is not just done through intervention with cell nuclei. The use of mRNA is another possible method. Anyone who saya otherwise is a criminal liar.
Also, even the very fact that cells are instructed to produce something foreign to them is genetic modification
A NOVEL MRNA MODIFICATION MAY IMPACT THE HUMAN GENETIC CODE
Deciphering the genetic code is a multi-step process that begins with transcribing information contained within DNA to a messenger RNA; the resulting mRNAs are then translated into proteins that comprise key components of the cell. It is known that RNA can be uniquely modified following the transcription process as a means to regulate function. This study provides a first example of a chemical modification to mRNA that enhances protein production. The investigators suggest the modification alters the efficiency by which the genetic code is read within each strand of mRNA.
The researchers focused on a specific chemical modification to mRNA, N4-acetylcytidine (ac4C). They first mapped the presence of ac4C to thousands of human mRNAs. In the lab the scientists next determined that the presence of ac4C within mRNAs powerfully enhanced their ability to be translated into protein. They further demonstrated that ac4C impacted cell proliferation, a hallmark of cancer cells.
“We hope to one day harness this discovery to specifically direct the modification to key mRNAs, thereby creating novel therapeutics,” said Dr. Oberdoerffer.
The researchers’ next steps are to map out how the modification specifically functions to alter gene expression as well as to determine if misregulation is a root cause of certain diseases.
https://ccr.cancer.gov/news/article/a-novel-mRNA-modification-may-impact-the-human-genetic-code