Is the Syrian Air space "safe" for US plane to fly over now?
Well Turkey, Iran and Russian are in cahoot.
http://www.euronews.com/2018/04/28/russia-iran-and-turkey-continue-to-seek-political-solution-in-syria
Turkey just got S400 air defence, and they are actively cooperating in Syria
https://www.usnews.com/news/world/articles/2018-04-14/putin-erdogan-discuss-bilateral-efforts-on-syria-kremlin
Syria is a cluster fuck the US should avoid.