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Pfizer.
Nigeria Trovafloxacin lawsuit
Main article: Abdullahi v. Pfizer, Inc.
In 1996, an outbreak of measles, cholera, and bacterial meningitis occurred in Nigeria. Pfizer representatives and personnel from a contract research organization (CRO) traveled to Kano to set up a clinical trial and administer an experimental antibiotic, trovafloxacin, to approximately 200 children.[175] Local Kano officials reported that more than fifty children died in the experiment,' while many others developed mental and physical deformities.'[176] The nature and frequency of both fatalities and other adverse outcomes were similar to those historically found among pediatric patients treated for meningitis in sub-Saharan Africa.[177] In 2001, families of the children, as well as the governments of Kano and Nigeria, filed lawsuits regarding the treatment.[178] According to the news program Democracy Now!, "[r]esearchers did not obtain signed consent forms, and medical personnel said Pfizer did not tell parents their children were getting the experimental drug."[179] The lawsuits also accuse Pfizer of using the outbreak to perform unapproved human testing, as well as allegedly under-dosing a control group being treated with traditional antibiotics in order to skew the results of the trial in favor of Trovan.
While the specific facts of the case remain in dispute, both Nigerian medical personnel and at least one Pfizer physician have stated that the trial was conducted without regulatory approval.
Pfizer is a leading member of the U.S. Global Leadership Coalition, a Washington D.C.-based coalition of over 400 major companies and NGOs that advocates for a larger International Affairs Budget, which funds American diplomatic, humanitarian, and development efforts abroad.[194]
Pfizer is one of the single largest lobbying interests in United States politics. For example, in the first nine months of 2009 Pfizer spent over $16.3 million on lobbying US congressional lawmakers, making them the sixth largest lobbying interest in the US (following Pharmaceutical Research and Manufacturers of America (PhRMA), which ranked fourth but also represents many of their interests). A spokeswoman for Pfizer said the company "wanted to make sure our voice is heard in this conversation" in regards to the company's expenditure of $25 million in 2010 to lobby health care reform.[195]
According to U.S. State Department cables released by WikiLeaks, Pfizer "lobbied against New Zealand getting a free trade agreement with the United States because it objected to New Zealand's restrictive drug buying rules and tried to get rid of New Zealand's former health ministerโ, Helen Clark, in 1990.[196]
Scott Gottlieb, who resigned as the US FDA Commissioner in April 2019, joined the Pfizer board of directors three months later, in July.
https://en.wikipedia.org/wiki/Pfizer#Environmental_record