If you have done your own “due diligence” in acquiring information on the experimental drug/therapy and your inclination is not to take it and you don’t want your future child to be saddled with any potential problems or side effects then I’d say do what you feel!
There is more science to back up your decision not to take it then there is in your wife’s doctors advice to take it. You/her doctor knows about as much about her that anons know just listening to ya. Doctors, for the most part, follow their associate’s advice more than then do “science” because they are lazy unethical frauds… with a PhD.
Doctors used to be individuals. Now they all form groups and practice as a single unit, with no diversity of opinion.