>>13805709
HIV has a SPIKE complex, just like Covid.
If [THEY] took parts of the HIV, ZIKA, SARS, CoV, etc, it would make sense.
The spike protein on the virus surface mediates its entry to the host cell and a high spike density promotes infection. HIV has a spike density that is almost two orders of magnitude lower than other viruses. This unique feature of HIV has defied explanation since it was first observed.
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1006408#:~:text=The%20spike%20protein%20on%20the,since%20it%20was%20first%20observed.
The SARS-CoV-2 spike glycoprotein is a focal point for vaccine immunogen and therapeutic antibody design, and also serves as a critical antigen in the evaluation of immune responses to COVID-19. A common feature amongst enveloped viruses such as SARS-CoV-2 and HIV-1 is the propensity for displaying host-derived glycans on entry spike proteins. Similarly displayed glycosylation motifs can serve as the basis for glyco-epitope mediated cross-reactivity by antibodies, which can have important implications on virus neutralization, antibody-dependent enhancement (ADE) of infection, and the interpretation of antibody titers in serological assays. From a panel of nine anti-HIV-1 gp120 reactive antibodies, we selected two (PGT126 and PGT128) that displayed high levels of cross-reactivity with the SARS-CoV-2 spike. We report that these antibodies are incapable of neutralizing pseudoviruses expressing SARS-CoV-2 spike proteins and are unlikely to mediate ADE via FcγRII receptor engagement. Nevertheless, ELISA and other immunoreactivity experiments demonstrate these antibodies are capable of binding the SARS-CoV-2 spike in a glycan-dependent manner. These results contribute to the growing literature surrounding SARS-CoV-2 S cross-reactivity, as we demonstrate the ability for cross-reactive antibodies to interfere in immunoassays.
https://www.biorxiv.org/content/10.1101/2021.01.03.425141v1.full