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https://www.msn.com/en-us/health/medical/doctors-in-india-are-reporting-covid-19-patients-with-gangrene-hearing-loss-and-diarrhea-but-there-s-not-enough-data-to-prove-they-re-caused-by-the-delta-variant/ar-AAL1tGu?ocid=msedgntp
Doctors in India are reporting COVID-19 patients with gangrene, hearing loss, and diarrhea - but there's not enough data to prove they're caused by the Delta variant
cschusterbruce@businessinsider.com (Dr. Catherine Schuster-Bruce,Swagata Yadavar) 1 hr ago
Doctors in India say COVID-19 patients have unusual symptoms that could be due to the Delta variant.
They include gangrene and hearing loss.
There aren't enough sequencing tests sent to labs to know if these are unique to the Delta variant.
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Doctors in India claim that the highly infectious Delta variant could cause unusual symptoms such as gangrene and hearing loss, which they say are becoming more common in COVID-19 patients of all ages.
Alarming details of the symptoms were reported by Bloomberg on June 7 and followed up by the Daily Mail and Daily Mirror in the UK, where the Delta variant now accounts for 91% of new COVID cases.
The highly infectious variant has spread to 67 countries and is becoming more common around the world. But, with fewer cases in India sequenced, there isn't enough data to know for sure whether the symptoms are unique to the variant, or are caused by COVID more generally, which has already been linked to unusual symptoms such as diarrhea and blood circulation issues.
The Delta variant is estimated to be 60% more infectious than the Alpha variant that's currently the most common in the US. It also has mutations that mean it can partially avoid the immune response.
Dr. Anthony Fauci, President Joe Biden's chief medical advisor, warned last week that the fast-spreading Delta variant could take hold in the US, if more Americans didn't get their COVID-19 shots. A Public Health England document from May reported the Pfizer and AstraZeneca vaccines were respectively 88% and 60% effective against the Delta variant after both doses.
Dr. Ganesh Manudhane, consultant cardiologist at Seven Hills Hospital in Mumbai, told Insider that he used to see four patients a year who had small blood clots causing gangrene, a serious condition where a loss of blood supply causes body tissue to die. Now it's one person every week, he said.
"I suspect it could be because of the Delta variant, because of the increased number of cases," Manudhane said - but he added that he hadn't genetically sequenced the patient's coronavirus tests to check for the Delta variant, which has become the most common COVID variant in the country since first being identified there in October.
Dr. Abdul Ghafur, infectious disease consultant at Apollo Hospital in Chennai told Insider that he had experienced far more cases of people with COVID-19 presenting with diarrhea than in the first wave in 2020.
This lack of data is holding back doctor's understanding of the variant.
Ghafur added that "despite having the second highest number of [COVID-19] patients in the world, India's premier research institute, the Indian Council of Medical Research, hadn't conducted any scientific studies of value."
Anurag Agarwal, director at the Institute of Genomics and Integrative Biology in Delhi, told Insider that there was no clear link between the Delta variant and atypical symptoms.
INSACOG, a group of research labs that conducts India's sequencing, said it had sequenced more than 10,000 samples since it was set up in December.
Barrett told the briefing there was no data to suggest the Delta variants caused different symptoms to other variants.
Black fungus
Black fungus isn't a symptom of coronavirus but a complication that occurs during the weeks after infection. Doctors in India have anecdotally associated it with the Delta variant.
Dr. Harsh Vardhan, India's health minister, said Monday that there were more than 28,000 recorded cases of black fungus infection that occurs in people with compromised immunity or diabetes. Of these, 86% had had COVID-19.
The link between black fungus and suppressed immunity or diabetes is not proven - but it's been suggested the high numbers of both in India could explain the number of cases of it.
Dr Shailesh Kothalkar, an ear, nose, and throat (ENT) surgeon at Seven Star Hospital in the western city of Nagpur, told the Telegraph that the Delta variant was "causing damage to the beta cells in the pancreas, which produce insulin and regulate blood glucose levels."
"We need more investigation into this but […] around 40% more patients are developing diabetes after having COVID-19 during this second wave," he said.
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delta variant