mRNA article from 2018
The second kind of RNA therapy focuses on replacing mRNA. Cystic fibrosis patients, for example, fail to make a functional protein called CFTR in their cell membranes. Scientists hope to have patients inhale particles containing healthy mRNA, replacing the dysfunctional CFTR protein in the lung. Translate Bio will start selling an mRNA candidate to treat patients with cystic fibrosis within the next several months, and another company, Moderna Therapeutics, is also developing a treatment for cystic fibrosis. Despite not having a single drug on the market, Moderna is valued at over $7.5 billion –demonstrating the enthusiasm for these strategies.