Pretty much in our faces the whole time.
Look carefully.
Family Guy, Season 14, Episode 3, "Guy, Robot"
God lifts nations up, and pushes nation down.
God plays Risk on a life-size board.
Blessed be the name of the Lord.
'''Around 190,000 PCR tests evaluated
Results alone unsuitable as a basis for pandemic measures'''
06/18/2021
In the renowned Journal of Infection *, researchers from the Medical Faculty of the UDE point out that the results of RT-PCR tests alone are insufficiently meaningful to justify measures to combat pandemics. According to their investigation, positive test results do not sufficiently prove that people infected with SARS-CoV-2 can infect other people with the coronavirus. Together with scientists from the University of MĂĽnster and the MVZ Labor MĂĽnster, they had previously evaluated around 190,000 results from more than 160,000 people.
The RT-PCR test technique is considered the gold standard when it comes to detecting an infection with the SARS-CoV-2 coronavirus. It can only be carried out in specialized facilities. During the pandemic, the results of corona tests using RT-PCR technology were and will be used to determine the number of nationwide new infections per 100,000 inhabitants (incidence).
This incidence value in turn forms an important basis for the federal and state governments to justify anti-corona measures, for example contact restrictions or curfews. However, the research teams from Essen and MĂĽnster question this based on their data analysis. "According to our study, a positive RT-PCR test alone is not sufficient proof that those tested can also transmit the coronavirus to other people," says first author Prof. Dr. Andreas Stang, Director of the Institute for Medical Informatics, Biometry and Epidemiology (IMIBE) at the Essen University Hospital. "The number of SARS-CoV-2 positive testers calculated at the end should therefore not be used as a basis for pandemic control measures such as quarantine, isolation or lockdown."
The authors therefore advise collecting or using data from other areas to assess the pandemic situation. "For example, reliable information on intensive care bed occupancy and mortality, i.e. the respective number of deaths in connection with COVID-19," suggests epidemiologist Prof. Stang, would be more suitable. In his area of ​​expertise, the consequences of epidemics on societies are examined.
The research team also talks about the possibility of improving the informative value of the RT-PCR value in future assessments of the pandemic situation by including the so-called cycle threshold value (Ct value). The number, also known as the threshold cycle value, can be used to make statements about the risk of infection by people who have tested positive. If the Ct value of those who tested positive is 25 or higher, it is currently assumed that they are no longer contagious because the viral load is too low. “On average, around 60% of those tested with COVID-19 symptoms were found to have such high CT values; In weeks 10 to 19 it was even 78% who were very probably no longer contagious, ”emphasizes Prof. Stang. "Querying the COVID-19 symptoms of those tested would also help,
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Original publication:
"The performance of the SARS-CoV-2 RT-PCR test as a tool for detecting SARS-CoV-2 infection in the population" https://doi.org/10.1016/j.jinf.2021.05.022
https://www.uni-due.de/2021-06-18-studie-aussagekraft-von-pcr-tests
The performance of the SARS-CoV-2 RT-PCR test as a tool for detecting SARS-CoV-2 infection in the population
Dear Editor,
Worldwide, detection and monitoring of SARS CoV-2 infection continues to be based on results of the real-time reverse-transcription polymerase chain reaction (RT-PCR) test.
A recent scoping review in this journal reported that assessment of the diagnostic accuracy of the RT-PCR test for SARS-CoV-2 has been less than perfect [1]. We analysed real-world data from a large laboratory in the city of MĂĽnster (population 313,000), Germany, derived from a single fully automated high throughput RT-PCR platform (cobas SARS-CoV-2 RT-PCR system, Roche Diagnostics) utilizing the same two gene targets for the entire study period (weeks 10-49, 2020).
This laboratory performed about 80% of all SARS-CoV-2 RT-PCR tests in the MĂĽnster region during this time. We explored changes in the percentage of positive RT-PCR tests (positive rate) over time. In addition, we assessed the influence of covariates such as age, sex, calendar time, and symptoms at the time of first RT-PCR test on the distribution of cycle threshold (Ct) values.
Nearly all swab specimens were tested within 24 hours of collection. The tests and their interpretation were carried out in accordance with the Roche cobas SARS-CoV-2 emergency use authorization (EUA) protocol, the specific targets of the test being the open reading frame (ORF) 1ab and the pan-Sarbecovirus E genes.
The limit of detection, defined as the concentration of analyte that will be detected in 95% of replicate tests was 0.007 median tissue culture infectious doses (TCID50) per ml for target 1 and 0.004 TCID50/ml for target 2, corresponding to Ct values of approximately 33 and 36, respectively (cobas® SARS-CoV-2 package insert, version 1.0).
RT-PCR tests that had not crossed the positivity threshold after the 40th cycle were reported as “negative”. The Ct value is inversely proportional to the initial amount of target nucleic acid and is thus a relative indicator of the concentration of viral particles in the clinical specimen. An increase in Ct value of three points indicates that the initial amount of viral particles was smaller by a factor of about ten.
We categorized our population-based Ct values according to the recommendations of the UK Office for National Statistics (ONS) COVID-19 household survey as < 25 and ≥ 25 [2].
Since there has been some discussion regarding this Ct-threshold [3, 4, 5], we performed a second categorization using a cutoff of < 30 versus ≥ 30. For a small subset of 58 people, sufficient clinical information was available to allow classification as symptomatic or asymptomatic.
Of 162,457 tested individuals, 4,164 (2.6%) had a positive RT-PCR test. The positive rate was lower among children aged 0-9 years (2.2%) and among adults aged 70 or more (1.6%), compared to the intermediate group aged 10-69 years (2.8%). The positive rate was strongly linked to the national SARS-CoV-2 test strategy. During the first and third phase of national testing, predominantly symptomatic people were tested. During these phases, the positive rates were higher than during the intermittent second phase corresponding to the summer season, when predominantly asymptomatic individuals were tested. The positive rate during the third phase was considerably higher than during the first phase. During the peak of testing asymptomatic individuals, only 0.4% tested positive with a mean Ct value of 28.8. Higher mean Ct values were observed among children aged 0-9 years (28.6) and adults above 70 years (27.0). Only 40.6% of positive tests showed Ct values below the threshold of 25, indicating a likelihood of the person being infectious (Table 1). In the small group of individuals for whom clinical information was available, symptomatic subjects had a markedly lower mean Ct value of 25.5 compared to asymptomatic subjects, who showed a mean Ct value of 29.6 (Figure 1).
>https://www.journalofinfection.com/article/S0163-4453(21)00265-6/fulltext
I know your opinion on the matter, sure.
And I know that you think YHWH was intended to be pronounced in a specific way, instead of what it actually is.
Intentionally unpronounceable, as the people who coined it were deathly afraid of mispronouncing the name of God, and thus, in their minds, committing blasphemy.
Hence shortcuts like HaShem, The Name, and YHWH, to be read but not spoken.
We need POTUS to make us our own federal holiday when he gets back into office.
Kunteenth.
Coincident with Juneteenth is fine too.
Gitmo.
Any autists had their coffee yet?
People mock the ancients for connecting demons with diseases.
As though such a connection were impossible, or refuted by observing germs.
And?
kek! Dan will love this.
It just bugs me. Seth Macfarland said that fans clamored for his show to be reinstated back on the air, and so many fans wanted it that it got put back on the air. But the first three seasons sucked. 1999, 2000, 2001. It had to be astroturfed. And now he's basically a billionaire.
Seth also said he had a hangover and was 10 minutes late getting to the gate to get on one of the planes involved in 9/11. And so missed the flight.
Look at the themes in Family Guy.
Pedophilia with Stewie, constantly, bestiality with the dog, homosexuality on parade, glorifying transgender with Quagmire's dad, rape, incest, murder, etc., etc., etc.
One set of blocks does say JIDF.
One says ABC
And the third says MOS
Nope, -1 for self checking.
Time for her to take a vacation.