Childhood trauma (such as circumcision) and hypersensitivity of the amygdala and frontal lobe dysfunction.
https://www.blueknot.org.au/Resources/Information/Understanding-abuse-and-trauma/What-is-childhood-trauma/Childhood-trauma-and-the-brain#:~:text=Children%20and%20adults%20who%20have,for%20learning%20and%20problem%20solving.