Anonymous ID: f788c8 July 5, 2021, 7:57 p.m. No.14063443   🗄️.is 🔗kun   >>3456 >>3584 >>3672 >>3712

I posted late last bread >>14063396 It seems related to:

The ACTUAL CONTENTS Inside Pfizer Vials EXPOSED!

https://rumble.com/vjgmj9-breaking-discovery-the-actual-contents-inside-pfizer-vials-exposed.html >>14062746 pb

 

PEGylated nano-graphene oxide as a nanocarrier for delivering mixed anticancer drugs to improve anticancer activity

 

https://web.archive.org/web/20210706024133/https://www.nature.com/articles/s41598-020-59624-w

 

Due to their high specific surface area, graphene oxide and graphene oxide-base nanoparticles have great potential both in dual-drug delivery and combination chemotherapy.

Anonymous ID: f788c8 July 5, 2021, 8:26 p.m. No.14063584   🗄️.is 🔗kun   >>3599 >>3672 >>3712 >>3844 >>4030 >>4169 >>4223 >>4245 >>4254 >>4260 >>4273

>>14063443

>>14063456

 

Recent progress of graphene oxide as a potential vaccine carrier and adjuvant

 

Graphene oxide (GO), widely employed for the delivery of biomolecules, excels in loading and delivering antigen and shows the potentiality of activating the immune system. However, GO aggregates in biological liquid and induces cell death, and it also exhibits poor biosolubility and biocompatibility. To address these limitations, various surface modification protocols have been employed to integrate aqueous compatible substances with GO to effectively improve its biocompatibility. More importantly, these modifications render functionalized-GO with superior properties as both carriers and adjuvants. Herein, the recent progress of physicochemical properties and surface modification strategies of GO for its application as both carriers and adjuvants is reviewed.

 

https://web.archive.org/web/20210706032353/https://www.sciencedirect.com/science/article/abs/pii/S1742706120303305?via%3Dihub

Anonymous ID: f788c8 July 5, 2021, 8:47 p.m. No.14063672   🗄️.is 🔗kun   >>3712 >>3844 >>4030 >>4169 >>4223 >>4245 >>4254 >>4260 >>4273

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>>14063443

>>14063456

 

Thrombus inducing property of atomically thin graphene oxide sheets

 

Here we report for the first time that atomically thin GO sheets elicited strong aggregatory response in platelets through activation of Src kinases and release of calcium from intracellular stores. Compounding this, intravenous administration of GO was found to induce extensive pulmonary thromboembolism in mice. Prothrombotic character of GO was dependent on surface charge distribution as reduced GO (RGO) was significantly less effective in aggregating platelets. Our findings raise a concern on putative biomedical applications of GO in the form of diagnostic and therapeutic tools where its prothrombotic property should be carefully investigated.

 

https://web.archive.org/web/20210706034440/https://pubmed.ncbi.nlm.nih.gov/21574593/

Anonymous ID: f788c8 July 5, 2021, 8:57 p.m. No.14063712   🗄️.is 🔗kun   >>3844 >>4030 >>4169 >>4223 >>4245 >>4254 >>4260 >>4273

>>14063672

>>14063584

>>14063443

>>14063456

Effects of Graphene Oxide Nanoparticles on the Immune System Biomarkers Produced by RAW 264.7 and Human Whole Blood Cell Cultures.

 

Graphene oxide nanoparticles (GONPs) have attracted a lot of attention due to their many applications… The current study shows that GONPs modulate immune system biomarkers and that these may pose a health risk to individuals exposed to this type of nanoparticle.

 

https://web.archive.org/web/20210706035342/https://europepmc.org/article/PMC/5853756