tRNA

BNT162b2 Vaccine: Possible Codons Misreading, Errors in Protein Synthesis and Alternative Splicing's Anomalies

(BioNTech, Pfizer vaccine)

Not sure what this all means, but it doesn't sound good - (Jan 2021)

Possible long-term risks on human health - medifags?

We can say that besides not being optimized, the sequence presents strong doubts about the presence of codon usage errors. It’s possible to hypothesize that an excessive alteration aimed at an extreme increase in protein expression may be the source of errors in the assembly of the mRNA gene sequence.

Altering tRNA availability can lead to neurodegenerative diseases and up regulation of specific tRNAs drives metastasis by enhancing stability of transcripts enriched in their cognate codons [5].

Mistranslation has very serious consequences on the pathophysiology of a variety of diseases, including multiple sclerosis, neurodegeneration, mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes, Parkinson's disease, and cancer (genesis, growth acceleration and metastasis) [6].

The correlation between the speed of protein synthesis, increased by 100%, with the translation errors of the sequence, as well as the mechanism that affects the production of amino acids remain in this case for now obscure, being many trials have not yet been performed.

https://www.longdom.org/open-access/bnt162b2-vaccine-possible-codons-misreading-errors-in-protein-synthesis-and-alternative-splicings-anomalies-61718.html