Anonymous ID: 835483 Aug. 1, 2021, 7 p.m. No.14248187   🗄️.is 🔗kun   >>8217 >>8218 >>8223 >>8230 >>8297 >>8316 >>8426

Look over the diagram

See where it says CO?

See where it says FeV?

If you had truly dug to find the meaning of COVFEFE

Don't you think you may have stumbled across this?

 

https://en.m.wikipedia.org/wiki/Cytochrome_P450

 

The active site of cytochrome P450contains a heme-iron center. The iron is tethered to the protein via a cysteine thiolate ligand. This cysteine and several flanking residues are highly conserved in known CYPs, and have the formal PROSITE signature consensus pattern [FW] - [SGNH] - x - [GD] - {F} - [RKHPT] - {P} - C - [LIVMFAP] - [GAD].[12] Because of thevast variety of reactions catalyzed by CYPs, the activities and properties of the many CYPs differ in many aspects.[13] In general, the P450 catalytic cycle proceeds as follows:

 

I highlighted the important parts.

Heme, because Malaria impairs heme metabolism and malaria medicines fix this. In other words, malaria medicine is not a bullet against the microorganism, instead it stops disruption of heme biochemistry

 

As with other quinoline antimalarial drugs, the antimalarial mechanism of action of quinine has not been fully resolved. The most accepted model is based on hydrochloroquinine and involves the inhibition of hemozoin biocrystallization, which facilitates the aggregation of cytotoxic heme. Free cytotoxic heme accumulates in the parasites, causing death

 

Cytochrome P450-mediated metabolism of vitamin D

 

https://www.jlr.org/article/S0022-2275(20)31738-7/fulltext

 

And lets not forget that exposure to sunlight allows the body to convert LDL cholesterol into Vitamin D. That's why the Cabal calls it BAD Cholesterol because you don't get sick and pay your life savings into their Big Pharma products

 

The vitamin D signal transduction system involves a series of cytochrome P450-containing sterol hydroxylases to generate and degrade the active hormone, 1α,25-dihydroxyvitamin D3, which serves as a ligand for the vitamin D receptor-mediated transcriptional gene expression described in companion articles in this review series. This review updates our current knowledge of the specific anabolic cytochrome P450s involved in 25- and 1α-hydroxylation, as well as the catabolic cytochrome P450 involved in 24- and 23-hydroxylation steps, which are believed to initiate inactivation of the vitamin D molecule. We focus on the biochemical properties of these enzymes; key residues in their active sites derived from crystal structures and mutagenesis studies; the physiological roles of these enzymes as determined by animal knockout studies and human genetic diseases; and the regulation of these different cytochrome P450s by extracellular ions and peptide modulators. We highlight the importance of these cytochrome P450s in the pathogenesis of kidney disease, metabolic bone disease, and hyperproliferative diseases, such as psoriasis and cancer; as well as explore potential future developments in the field.

Anonymous ID: 835483 Aug. 1, 2021, 7:04 p.m. No.14248217   🗄️.is 🔗kun   >>8226 >>8273 >>8297 >>8316 >>8426

>>14248187

Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases

 

Abstract

Glyphosate, the active ingredient in Roundup®, is the most popular herbicide used worldwide. The industry asserts it is minimally toxic to humans, but here we argue otherwise. Residues are found in the main foods of the Western diet, comprised primarily of sugar, corn, soy and wheat. Glyphosate's inhibition of cytochrome P450 (CYP) enzymes is an overlooked component of its toxicity to mammals. CYP enzymes play crucial roles in biology, one of which is to detoxify xenobiotics. Thus, glyphosate enhances the damaging effects of other food borne chemical residues and environmental toxins. Negative impact on the body is insidious and manifests slowly over time as inflammation damages cellular systems throughout the body. Here, we show how interference with CYP enzymes acts synergistically with disruption of the biosynthesis of aromatic amino acids by gut bacteria, as well as impairment in serum sulfate transport. Consequences are most of the diseases and conditions associated with a Western diet, which include gastrointestinal disorders, obesity, diabetes, heart disease, depression, autism, infertility, cancer and Alzheimer’s disease. We explain the documented effects of glyphosate and its ability to induce disease, and we show that glyphosate is the “textbook example” of exogenous semiotic entropy: the disruption of homeostasis by environmental toxins

 

You are not crazy, they really are out to get you. Big Chemistry makes the pesticides, Big Agribusiness sprays it on the food, Big Media encourages you to eat the highly processed poisonous foods and Big Pharma sells you the drugs when you inevitably get sick

Anonymous ID: 835483 Aug. 1, 2021, 7:14 p.m. No.14248273   🗄️.is 🔗kun   >>8371

>>14248217

 

We have learned that using a disinfectant internally is better than externally. Chlorine Dioxide commonly used in hospitals for cleaning EVERYTHING!!! can be sprayed in the sinuses if you get a properly cleanly produced chemical and use the right weak dilution level. Bolivia is doing this. IN Japan they have discovered that a very low level of Chlorine Dioxide gas in the air is very effective.

 

But UV radiation might be a better way overall. It was once common.

 

Ultraviolet Irradiation of Blood: “The Cure That Time Forgot”?

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122858/

 

Abstract

Ultraviolet blood irradiation (UBI) was extensively used in the 1940s and 1950s to treat many diseases including septicemia, pneumonia, tuberculosis, arthritis, asthma and even poliomyelitis. The early studies were carried out by several physicians in USA and published in the American Journal of Surgery. However with the development of antibiotics, UBI use declined and it has now been called “the cure that time forgot”. Later studies were mostly performed by Russian workers and in other Eastern countries and the modern view in Western countries is that UBI remains highly controversial.

 

This chapter discusses the potential of UBI as an alternative approach to current methods used to treat infections, as an immune-modulating therapy and as a method for normalizing blood parameters. No resistance of microorganisms to UV irradiation has been reported, and multi- antibiotic resistant strains are as susceptible as their wild-type counterparts. Low and mild doses of UV kill microorganisms by damaging the DNA, while any DNA damage in host cells can be rapidly repaired by DNA repair enzymes. However the use of UBI to treat septicemia cannot be solely due to UV-mediated killing of bacteria in the blood-stream, as only 5–7% of blood volume needs to be treated with UV to produce the optimum benefit. UBI may enhance the phagocytic capacity of various phagocytic cells (neutrophils and dendritic cells), inhibit lymphocytes, and oxidize blood lipids. The oxidative nature of UBI may have mechanisms in common with ozone therapy and other oxygen therapies. There may be some similarities to extracorporeal photopheresis (ECP) using psoralens and UVA irradiation. However there are differences between UBI and ECP in that UBI tends to stimulate the immune system, while ECP tends to be immunosuppressive. With the recent emergence of bacteria that are resistant to all known antibiotics, UBI should be more investigated as an alternative approach to infections, and as an immune-modulating therapy.

 

Mechanisms of Action of UBI

One of the major obstacles that UBI has consistently faced throughout the almost 90 years

since the first patient was treated has been the lack of understanding of the mechanisms of

action. Over the years its acceptance by the broad medical community has been hindered by

this uncertainty. Confusion has been caused by the widely held idea that since UV is used

for sterilization of water and surgical instruments; therefore its use against infection must

also rely on UV-mediated direct destruction of pathogens. Another highly confusing aspect

is the wide assortment of diseases, which have been claimed to be successfully treated by

UBI. It is often thought that something that appears to be “too good to be true” usually is.

UBI affects various functions of red blood cells and various different leukocytes as has been

proven in various in vitro studies. A common model is stimulator cells in mixed leukocyte

cultures; another is helper cells in mitogen- stimulated cultures. UV also reversed cytokine

production and blocked cytokine release. UV can also disturb cell membrane mobilization

(Fig. 25.3).

Anonymous ID: 835483 Aug. 1, 2021, 7:23 p.m. No.14248371   🗄️.is 🔗kun   >>8386

>>14248273

Inactivation of Airborne Bacteria and Viruses Using Extremely Low Concentrations of Chlorine Dioxide Gas

 

https://pubmed.ncbi.nlm.nih.gov/26926704/

 

Abstract

Infectious airborne microbes, including many pathological microbes that cause respiratory infections, are commonly found in medical facilities and constitute a serious threat to human health. Thus, an effective method for reducing the number of microbes floating in the air will aid in the minimization of the incidence of respiratory infectious diseases. Here, we demonstrate that chlorine dioxide (ClO2) gas at extremely low concentrations, which has no detrimental effects on human health, elicits a strong effect to inactivate bacteria and viruses and significantly reduces the number of viable airborne microbes in a hospital operating room. In one set of experiments, a suspension of Staphylococcus aureus, bacteriophage MS2, and bacteriophage ΦX174 were released into an exposure chamber. When ClO2 gas at 0.01 or 0.02 parts per million (ppm, volume/volume) was present in the chamber, the numbers of surviving microbes in the air were markedly reduced after 120 min. The reductions were markedly greater than the natural reductions of the microbes in the chamber. In another experiment, the numbers of viable airborne bacteria in the operating room of a hospital collected over a 24-hour period in the presence or absence of 0.03 ppm ClO2 gas were found to be 10.9 ± 6.7 and 66.8 ± 31.2 colony-forming units/m3 (n = 9, p < 0.001), respectively. Taken together, we conclude that ClO2 gas at extremely low concentrations (≤0.03 ppm) can reduce the number of viable microbes floating in the air in a room. These results strongly support the potential use of ClO2 gas at a non-toxic level to reduce infections caused by the inhalation of pathogenic microbes in nursing homes and medical facilities.

 

PDF attached

Anonymous ID: 835483 Aug. 1, 2021, 7:26 p.m. No.14248386   🗄️.is 🔗kun

>>14248371

Here the mayor of a town in Bolivia recounts how they used Chlorine Dioxide solution produced by a Bolivian university to cure COVID cases in their town.