https://web.archive.org/web/20040704012556/http://www.who.int/tdr/publications/publications/comdti.htm

Community Directed Treatment with Ivermectin

Report of a multi-country study

Onchocerciasis remains a serious public health in large parts of tropical Africa where some 18 million people are affected. The most severe consequence of onchocerciasis is blindness, which may afflict over one third of the adult population of the most affected communities. Other important problems are severe skin disease and maddening itching which cause great suffering to millions of people.

https://web.archive.org/web/20131029051213/https://www.who.int/apoc/cdti/history/en/

How community-directed treatment with ivermectin (CDTI) began

The treatment for onchocerciasis is ivermectin (Mectizan®). In 1987 the manufacturers of the drug –Merck & Co., Inc. – pledged to provide an unlimited supply of ivermectin free of charge to all those at risk from onchocerciasis and for as long as necessary. With drug supplies secured, the challenge for onchocerciasis control programmes was to work out a way to deliver the treatment to the people who needed it, and to sustain the delivery for a sufficiently long period to bring about control of the disease.

Community-directed treatment with ivermectin

There were some basic requirements for the ivermectin distribution system:

it had to be cheap,

it had to work in some of the most difficult, remote, war-torn areas of Africa, many of which were far from urban health centres,

it had to be sustainable – to break transmission of the parasite, ivermectin has to be given once a year for 16–18 years to all eligible populations at high risk.

CDTI timeline

1988: OCP use mobile teams of health workers to distribute ivermectin. There is very little community involvement and costs to the health system are high.

1995: Experts at WHO, the World Bank, and the UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR) recruit a team of African scientists to find a more sustainable and cost-effective method to deliver the treatment.

1996: Results from a multi-country study show that community-directed treatment is a feasible, effective and sustainable approach.

1997: APOC formally adopts the CDTI strategy, which proves to be a huge success.

https://apps.who.int/iris/bitstream/handle/10665/43545/9241547103_eng.pdf

Recommended intervention strategy and aim Yearly distribution of ivermectin to meso- and hyperendemic communities is the standard option. However, drug distribution may take place more frequently: in some countries, the national plans recommend treatment every 6 months (aiming at controlling morbidity and eventually interrupting transmission). Control activities are organized on a regional basis as outlined in the following paragraphs:

Onchocerciasis Control Programme (OCP). OCP was launched in 1974 and officially closed in 2002. Its goal was to eliminate onchocerciasis as a public health problem and an obstacle to socioeconomic development from 11 west African countries. Vector control was the main strategy – and the only strategy from 1974 to 1988. From 1988 (when the Mectizan® Donation Program was established) until 2002, vector control was coupled with mass distribution of ivermectin. Vector control is continuing in five countries (Benin, Ghana, Guinea, Sierra Leone and Togo) of the former OCP, known as Special Intervention Zones. In all the 11 countries, detection of transmission recrudescence and disease control through IVM distribution are now routine functions of national disease surveillance and control services. African Programme for Onchocerciasis Control (APOC). APOC’s goal is to eliminate onchocerciasis as a disease of public health importance and an important constraint on socioeconomic development in 19 African countries. Community-directed treatment with ivermectin (CDTI) is the main strategy of APOC, coupled with vector control in four selected foci in Equatorial Guinea (1 focus), United Republic of Tanzania (1 focus) and Uganda (2 foci). Onchocerciasis Elimination Program for the Americas (OEPA). The goal of OEPA is elimination of onchocerciasis as a public health problem, defined as elimination of morbidity – and interruption of transmission where feasible – in six endemic countries in the Americas (Brazil, Colombia, Ecuador, Guatemala, Mexico and Venezuela) through mass treatment with ivermectin.

https://www.washingtontimes.com/news/2021/aug/30/convicted-rapist-reached-us-afghan-evacuation-flig/

Convicted rapist reached the U.S. on Afghan evacuation flight

https://www.washingtontimes.com/news/2021/sep/3/dhs-confirms-people-watch-lists-among-those-evacua/

DHS confirms people on watch lists among those evacuated from Afghanistan

https://apnews.com/article/middle-east-child-trafficking-27d93a340c4834d497eb36e22bb72f42

Afghan evacuation raises concerns about child trafficking

https://www.canada.ca/en/public-health/news/2021/08/government-of-canada-announces-funding-for-covid-19-safe-voluntary-isolation-sites-in-ontario.html

Government of Canada Announces Funding for COVID-19 Safe Voluntary Isolation Sites in Ontario

“Protecting Canadians from COVID-19 and helping stop the spread is a community effort. The Safe Voluntary Isolation Sites Program supports municipalities across Canada, including these projects in Ontario, so they can assist residents with safe places for self-isolation.”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3043740/

Ivermectin, ‘Wonder drug’ from Japan: the human use perspective

https://grrrgraphics.com/wp-content/uploads/2021/09/horse_sense_and_cents-1.jpg

https://en.wikipedia.org/wiki/Blue_Mustang

>>14521730

You're telling me dogs/cats should smoke cigarettes?

It's the lack of opposable thumbs that poses the greatest challenge.

>>14521623

>leukemia

leuk-what?

>>14521769

https://streamable.com/9oo5b0

>>14521787

wow, that was really good