I keep wondering why Ivermectin works on CoVID…

A friend of mine, who lives in a rural community, was fully vaccinated, became extremely ill (thought it was COVID). I asked if he got tested for it, and he said no. It turns out, he had the “Giardia” parasite (AKA Beaver Fever)

Got looking into it, and there is something strange going on with parasites, viruses and vaccines – Giardia is present in a lot of cases of COVID, can cause Cytokine Production, may be used as an adjuvant, as a vaccine (jab, oral, mucosal, DNA) etc. It isn’t the only parasite being used in this manner.

Giardia Parasite

A common gut bug has evolved an ingenious strategy to outwit the immune system, helping to conceal the parasite from immune attack.

Here is a short list of excerpts:

• Uses RNA Interference

• Demonstrated that the siRNAs could effectively and specifically inhibit gene expression of Spike protein in SARS-CoV-infected cells

• Canonical microRNAs could not be identified in this parasite

• This altered parasite, they hope, should serve as the perfect vaccine

• Evidence that Entamoeba and Giardia are hosts of CRESS viruses, via networks of viral recombination anchored to specific hosts

• The eukaryotic CRESS-DNA viruses are associated with a variety of diseases. DNA Viruses (wasting disease, bird flu etc)

• We reported parasitic infections in 72.8% of mild COVID-19 cases and 20.7% of severe cases. Toxoplasma gondii, Cryptosporidium, Blastocyst, and Giardia were the most common parasitic infections among the COVID-19 cases studied.

• Causes disturbances in zinc metabolism of infected children, representing a risk factor for zinc deficiency

• Acute fulminant eosinophilic myocarditis is a rare disorder - In this case, eosinophilic myocarditis was associated with Giardia lamblia infection

• Genetic engineering of the OMV‐producing bacteria can be used to improve and expand their usefulness as vaccines

• We have identified novel adjuvant activity in specific cytosol fractions from trophozoites of Giardia isolate Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins

• Giardia duodenalis Induces Proinflammatory Cytokine Production in Mouse Macrophages

• Mucosal delivery of a transmission-blocking DNA vaccine encoding Giardia lamblia

• Discovery of a specific double-stranded RNA virus in Giardia lamblia

Continued…..

>>14523968

#2

Giardia Parasite

A common gut bug has evolved an ingenious strategy to outwit the immune system, helping to conceal the parasite from immune attack.

Writing in this week's Nature an Argentinian research team led by Hugo Lujan at the Catholic University at Cardoba found that Giardia lamblia, a major cause of intestinal infections worldwide, has a repertoire of 190 different coat proteins with which it can disguise itself. The organism selects a different coat every few generations, returning the previous outfit to the genomic wardrobe to wear again in the future.

By studying which genes were being turned on in Giardia the researchers found that the parasite uses a mechanism called RNA interference to suppress the action of the other 189 coat genes it's not using. The bug makes short sequences of the DNA-relative RNA, which are the genetic mirror-image of the un-used coat genes. These mirror-image RNAs lock on to their respective coat genes and prevent them from being expressed, keeping them in the closet.

https://www.thenakedscientists.com/articles/science-news/giardia-gene-shuffling-masks-bug-immunity

Giardia RNA interference/Gene Silencing

There are few studies employing RNAi in Giardia. Several elements of the RNAi silencing pathway have been identified in Giardia, making conceivable its existence and therefore its potential usefulness to perform specific gene silencing

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704216/

https://en.wikipedia.org/wiki/Gene_silencing

2004 - We constructed specific siRNAs targeting the S gene in SARS-CoV. We demonstrated that the siRNAs could effectively and specifically inhibit gene expression of Spike protein in SARS-CoV-infected cells. Our study provided evidence that RNAi could be a tool for inhibition of SARS-CoV.

https://pubmed.ncbi.nlm.nih.gov/14988013/

Surprisingly, we have found that two major types of sRNAs (i.e., endogenous siRNAs and tRNA-derived sRNAs) are largely encoded in the genome of G. lamblia, whereas canonical microRNAs could not be identified in this parasite.

https://www.pnas.org/content/111/39/14159

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>>14523980

#3

A Coat of Many Proteins May Be This Parasite’s Downfall

With this knowledge, they have accomplished a cunning counterploy: they have forced the parasite to make and wear all its coat proteins at the same time. This altered parasite, they hope, should serve as the perfect vaccine, because it immunizes the body to the full repertoire of giardia’s coat proteins all at once. The idea has worked well in animal tests, Dr. Luján said.

SHIFTY: When giardia must wear all its 190 coat proteins at once instead of selecting one and changing it often, it cannot hide from the immune system.

https://www.nytimes.com/2008/12/16/science/16giar.html

COVID-19 and parasitology

As far as protozoa are concerned, it is worth remembering that in the 1960s, electron microscopy began to show the presence of viral particles in several members of the Trypanosomatidae family, in Giardia, Trichomonas, and Cryptosporidium, among others (see Miles 1988; Charon et al. 2019). Several recent studies in different countries that used meta-transcriptomic analysis of blood from patients with malaria, as well as from transmitting mosquitoes, revealed the presence of a sequence similar to that of an RNA narnavirus (designated as Mathryoskha RNA virus 1) in Plasmodi um vivax, as well as in transmitting mosquitoes, but not in the blood of patients infected with P. falciparum or P. knowlesi. Third, because in critical moments, such as the one we are facing today, the scientific community is “summoned” by the government and society to give scientific answers to the countless questions that are raised.

https://link.springer.com/article/10.1007/s00436-020-06719-y

The eukaryotic CRESS-DNA viruses are associated with a variety of diseases. Plant viruses in the families Geminiviridae and Nanoviridae infect economically important crops, causing significant damage to agricultural productivity. Animal viruses in Circoviridae are associated with many diseases, including respiratory illness, intestinal illness, and reproductive problems. Bacilladnaviruses, which primarily infect diatoms, are thought to have a significant role in controlling algal blooms.[3]

Swine Flu?

https://en.wikipedia.org/wiki/Monodnaviria

While several studies have discussed or attempted to identify an association between viruses with circular Rep-encoding single-stranded DNA genomes (CRESS viruses) and gut parasites, no CRESS virus was known to infect any protozoan. Metagenomic virus discovery done by Kinsella et al provides the evidence that Entamoeba and Giardia are hosts of CRESS viruses, via networks of viral recombination anchored to specific hosts. This analysis reveals two CRESS virus families (Naryaviridae and Nenyaviridae) infecting Entamoeba parasites, while a third (Vilyaviridae) infects Giardia duodenalis. The trio - named after the after the three rings from Tolkien’s canon - supplements five CRESS virus families already known to infect eukaryotes, extending the CRESS virus host range to protozoa.

https://www.honours.eu/publications/entamoeba-and-giardia-parasites-implicated-as-hosts-of-cress-viruses

Ivermectin treatment

https://pubmed.ncbi.nlm.nih.gov/11478442/

The majority of the studied cases had chest manifestation either alone (54.7%) or in association with gastrointestinal (GIT) manifestations (19.7%), whereas 25.6% had GIT symptoms. We reported parasitic infections in 72.8% of mild COVID-19 cases and 20.7% of severe cases. Toxoplasma gondii, Cryptosporidium, Blastocyst, and Giardia were the most common parasitic infections among the COVID-19 cases studied.

Malaria-endemic countries have reported a low number of COVID-19 cases

https://gutpathogens.biomedcentral.com/articles/10.1186/s13099-021-00427-3

Giardiasis is a common yet neglected cause of acute-chronic diarrheal illness worldwide which causes disturbances in zinc metabolism of infected children, representing a risk factor for zinc deficiency

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488794/

In vitro findings indicate that Giardia-induced bacterial translocation is primarily paracellular, rather than transcellular, and implicate the degradation of tight junction proteins, including occludin and claudin-4.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836132/

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>>14523968

#4

Acute fulminant eosinophilic myocarditis is a rare disorder of unknown etiology characterized by diffuse or focal myocardial inflammation with eosinophilic infiltration (4, 5). Although several causes have been described in the literature, the exact cause of eosinophilic myocarditis is frequently unknown (6). In this case, eosinophilic myocarditis was associated with Giardia lamblia infection; after treatment with metronidazole therapy, the patient made a full recovery.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528500/

Paywall - Myocarditis in association with giardia intestinalis infection

https://www.internationaljournalofcardiology.com/article/S0167-5273(14)01752-5/fulltext

Genetic engineering of the OMV‐producing bacteria can be used to improve and expand their usefulness as vaccines.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768646/

OMVs might also be designed as an advanced mucosal delivery vehicle for use as a vaccine carrier.

These conclusive data could support vaccine engineering with the use of OMV adjuvants in animal and human trials in an attempt to control the spread of bacterial and viral infections.

https://www.frontiersin.org/articles/10.3389/fmicb.2018.00783/full

We have identified novel adjuvant activity in specific cytosol fractions from trophozoites of Giardia isolate BRIS/95/HEPU/2041 (J. A. Upcroft, P. A. McDonnell, and P. Upcroft, Parasitol. Today, 14:281–284, 1998). Adjuvant activity was demonstrated in the systemic and mucosal compartments when Giardia extract was coadministered orally with antigen to mice. Enhanced antigen-specific serum antibody responses were demonstrated by enzyme-linked immunosorbent assay to be comparable to those generated by the “gold standard,” mucosal adjuvant cholera toxin. A source of adjuvant activity was localized to the cytosolic component of the parasite. Fractionation of the cytosol produced fraction pools, some of which, when coadministered with antigen, stimulated an enhanced antigen-specific serum response. The toxic component of conventional mucosal adjuvants is associated with adjuvant activity; therefore, in a similar way, the toxin-like attributes of BRIS/95/HEPU/2041 may be responsible for its adjuvanticity. Complete characterization of the adjuvant is under way.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC98786/

Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins

https://www.nature.com/articles/s41467-018-08265-9

Giardia duodenalis Induces Proinflammatory Cytokine Production in Mouse Macrophages via TLR9-Mediated p38 and ERK Signaling Pathways

https://www.frontiersin.org/articles/10.3389/fcell.2021.694675/full

Mucosal delivery of a transmission-blocking DNA vaccine encoding Giardia lamblia

These results demonstrate, for the first time, the development of parasite transmission-blocking immunity at the intestinal level following the administration of a mucosal DNA vaccine delivered by S. typhimurium STM1.

https://pubmed.ncbi.nlm.nih.gov/17996337/

Discovery of a specific double-stranded RNA virus in Giardia lamblia

https://pubmed.ncbi.nlm.nih.gov/3807947/

Are There Parasites in the Pfizer "Vaccines"?

>>14517786

>>14524066

Maybe they are using this, or another genetically modified parasite as a carrier for something else, or to hide something..

From my understanding, it has kind of a 'shield' or protective coating