I don't think we can "throw in the towel."
Once you're awake you're always awake.
What you can do is take a break to refresh your mind, heart and soul.
Go fishing, do some gardening, trip to the ocean, a retreat. Whatever suits you.
If you believe in God, spend some quiet time with him. In the end. God wins. He promises a glorious ending for those that believe on His Son.