https://www.cdc.gov/mmwr/

Morbidity and Mortality Weekly Report

https://www.cdc.gov/mmwr/volumes/70/wr/mm7039e4.htm?s_cid=mm7039e4_w

During August 12–September 19, 2021, a total of 22,191 v-safe registrants reported receipt of an additional dose of COVID-19 vaccine after completing the primary series…

Local (16,615; 74.9%) and systemic (15,503; 69.9%) reactions were frequently reported during the week after an additional dose of COVID-19 vaccine, most commonly on the day after vaccination. Frequently reported reactions were injection site pain (15,761; 71.0%), fatigue (12,429; 56.0%), and headache (9,636; 43.4%).

Among 22,191 additional dose recipients, a total of 7,067 (31.8%) reported health impacts, and approximately 28.3% (6,287) reported they were unable to perform normal daily activities, most commonly on the day after vaccination. Medical care was sought by 401 (1.8%) registrants, and thirteen (0.1%) were hospitalized.