GUARANTEED permanent genetic modification down through generations. No going back without the original genetic sequence to re- introduce into an organism.
The selected genes are forced (driven) on to the next generation to be handed down continuously. whatever that selected trait may be. Even in Vevo it might be possible to manipulate an organism to spontaneously exhibit the new introduced genetic code.
Even recessive traits can know over power more dominant traits if already found within or introduced into an organism via CRISPR
Intelligence, physical traits, immune system etc.
Alter or suppress populations
Think: Island of Doctor Moreau
Raptorโฆโฆ bird of prey