>>1479483
>>1479565
>>1479570
>>1479576
deep, but stay with 23 and me for a moment:
>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1832087/
The genetic code is nearly optimal for allowing additional information within protein-coding sequences
We consider the ability of the genetic code to support, in addition to the protein-coding sequence, additional information that can carry biologically meaningful signals. These signals can include binding sequences of regulatory proteins that bind within coding regions
The real code aborts translation eight codons earlier than the average alternative code (15 codons vs. 23 codons). Conservative estimates suggest that such a difference, equivalent to a relative fitness advantage of about 10^-4, is readily selectable (see Methods).
The real code “saves” about 23–15 = 8 extra peptide bonds for each 30,000 translated peptide bonds, conveying an advantage of 8/30,000∼2 × 10^−4, and hence, saving 0.02% of the peptide bonds made by the organism.
This relative fitness advantage is much higher than minimal selectable fitness differences in microorganisms, which is on the order of 10^−7 to 10^−8.
WHY IS PROTEIN-CODING RELEVANT TO US & /qresearch/?
>https://hub.jhu.edu/2017/07/05/lasso-probe-clones-thousands-genes-at-once/
Scientists at Johns Hopkins, Rutgers, the University of Trento in Italy, and Harvard Medical School report they have developed a new molecular technique that can be used to isolate thousands of long DNA sequences at the same time, more than ever before possible.
According to the researchers, the new technology—known as LASSO cloning—speeds up the creation of proteins, the final products of genes, and is likely to lead to far more rapid discovery of new medicines and biomarkers for scores of diseases.
HISTORICALLY, FIGURING OUT WHAT A GENE DOES BY CLONING ITS DNA AND EXPRESSING ITS PROTEIN WAS DONE ONE GENE AT A TIME.
THE NEW TECHNOLOGY SIMULTANEOUSLY CLONES AND EXPRESSES THOUSANDS OF PROTEIN-CODING DNA SEQUENCES IN A SINGLE REACTION.
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<Think Big Pharma, RIP