"The Food and Drug Administration seems likely to allow Americans to switch vaccines when choosing a COVID-19 booster shot. That authorization, which could come this week, is the latest development in a long-running debate over whether a mix-and-match strategy helps protect people from the coronavirus. On Friday, the FDA advisers voted in favor of authorizing a second dose of Johnson & Johnson’s vaccine as a booster, to strengthen immunity in Americans who had received the first dose. But Dr. Peter Marks, the FDA’s top vaccine regulator, said at the meeting that it was possible the agency would not require people to take the same vaccine as a booster. The agency is considering adjusting the language on the labels for all three authorized vaccines to indicate that providers can administer a different authorized vaccine at their discretion. If COVID-19 boosters become an annual event, then a mix-and-match strategy should help enable more people to get vaccinated. It will be far easier for people to get regularly immunized if they do not have to worry about receiving another shot of their original vaccine."
https://www.seattletimes.com/nation-world/nation/mix-and-match-covid-boosters-why-they-just-might-work/