You need to start treat this physically. Supplements, supplements, supplements. Plus healthy eating.
Ashwagandha, B-Complex vitamins, Magnesium, L-Theanine, Vitamin D, Melatonin, Rhodiola, Fish/Flaxseed Oil, Valerian Root, Kava, Glycine are all good places to start.
Stress and depression is not just mental. Prayers to you and spouse anon.