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Associate Attorney General Rachel Brand resigns to take a job with Walmart. who will succeed her might portend for the future of special counsel Robert Mueller’s investigation into Russian interference in the 2016 election.While assistant associate attorneys general typically do not make headlines, Brand’s departure raises questions about who will succeed her.

The reason why all of this matters is because the associate attorney general is the designated successor to the Justice Department’s second-highest ranking official, Deputy Attorney General Rod Rosenstein. And it is Rosenstein, thanks to the recusal of Attorney General Jeff Sessions, who authorized Mueller’s investigation in the first place — and who is the only government official with the legal authority to directly fire Mueller and otherwise terminate his investigation. In other words, Rosenstein is the crucial fulcrum between the political leadership of the Trump administration and the quasi-independent special counsel. The president cannot directly interfere with the special counsel’s investigation without going through — or getting rid of — Rosenstein.

To be sure, various Republicans in Congress have expressed their support for both Mueller and Rosenstein, but there have been increasing signals from the White House in recent weeks that Rosenstein may be in the crosshairs — including as a potential casualty of the faux #ReleaseTheMemo scandal. And if Rosenstein resigns or is fired, it would usually be the associate attorney general who would inherit his authority vis-à-vis Mueller. Now, however, that honor would fall to the person next in line to act as attorney general — in this case, Francisco.

Simply put, if the president were to fire Rosenstein tomorrow, Solicitor General Noel Francisco would take over supervision of Mueller and his investigation. Thus, for those worried that the president might try to prevent the Russia investigation from running its course, Brand’s resignation reduces the number of Senate-confirmed officials who would have to agree with the president (or whom the president would have to fire) to bring about that result. In this case, Brand was an official generally perceived to be deeply faithful to the rule of law — and therefore unlikely to interfere with Mueller’s investigation without good cause.

Of course, Senate confirmation ensures neither integrity nor loyalty. Someone confirmed to a senior Justice Department post is not automatically less likely to do the president’s bidding than someone temporarily assigned to that position without Senate approval. After all, it was then-Solicitor General Robert Bork who famously complied with President Richard Nixon’s order to fire the Watergate special prosecutor after Nixon’s attorney general and deputy attorney general both refused (and resigned) — a sequence of events that’s come to be known as the “Saturday Night Massacre.”

But as that episode underscores, the more officials who have to be forced out before the president can achieve a particular result, the greater the political costs. And so with every presumably voluntary departure of someone like Brand, the political costs of direct presidential interference with the Russia investigation may well go down.

But even if Brand’s departure ends up having no bearing on the Russia investigation, specifically, it’s still an ominous sign more generally. After less than nine months, the third-ranking official in the Justice Department resigned, according to an associate, “[b]ecause she is very smart, accomplished, and talented, and wants to protect her career.” If someone as smart and accomplished as Brand came to the conclusion that the best way to protect her career was to leave the Trump administration, one can only imagine — the Russia investigation aside — exactly what she is trying to protect her career from.