this is an insult to office space
Study identifies potential biomarkers for urine test for bile duct cancer
15 November 2021
Early-stage research has found 10 metabolites associated with bile duct cancer which might one day help create a urine test to identify the cancer. The work is the result of a collaboration between Imperial College London and the Khon Kaen University in Thailand, who are working together to understand and reduce the disproportionately high rates of bile duct cancer in the Isaan peoples from the North-Eastern region of Thailand and Laos. The research is published in the journal Scientific Reports. In the UK, bile duct cancer is rare, with around two in every 100,000 people developing it, and the cause is unknown. However, in Thailand it affects more than 30 times that figure in the North-Eastern region alone (85 cases in every 100,000 people) with still higher figures across the river in Laos. In Thailand, bile duct cancers are associated with theO. viverrini parasitewhich may be inadvertently eaten in raw, partially cooked, or fermented fish dishes. Theparasiteenters the bile ducts and causes damage which can then lead to cancer. “Early detection of bile duct cancer is vital as it is often symptomless. This means it is often recognised late when it is hard to treat and surgery to remove the cancer is not possible. Other than surgery there are no currently effective treatments for bile duct cancer.” says Professor Simon Taylor-Robinson, senior author of the study, and Imperial’s Envoy for International Affairs.
The study included 34 participants from Thailand and 32 participants from the UK, including 14 participants with bile duct cancer in the Thai group and 10 in the UK group. The researchers note that the rarity of the cancer meant a bigger study wasn’t possible. The participants provided urine samples which were assessed using liquid chromatography mass spectroscopy - a technique that separates and detects molecular components in a sample. This allowed the researchers to identify the metabolites in the participants’ urine. While there were differences in the metabolites of the Thai and UK participants due to diet and weight, the researchers found 10 metabolites which appear to be related to the development of the types of cancers seen in both groups. This may indicate that the different forms of bile duct cancer act in the same way in the body, the scientists say. This could mean that any test developed using these metabolites could be used universally, if proven successful. The researchers say the next step of their research will be to create a test based on the metabolites, and see if it can accurately identify bile duct cancers in a clinical trial. This will also help them understand how the cancer develops.
https://www.imperial.ac.uk/news/231896/study-identifies-potential-biomarkers-urine-test/
TL;DR
>parasites cause bile duct cancer (in reality all cancers)
>bile duct cancer is "symptomless" and often detected late stage
>metabolites indicating the possibility of bile duct cancer is found in the urine (seems straight forward)
>a standard test for the cancer indicating metabolites needs to be established
>for more discussion on deparasiting see 8kun.top/wagmi