(Please read from the start)
“Accession of James II and VII
When Charles II died in 1685, Anne's father became King James II of England and VII of Scotland. […].
In early 1687, within a matter of days, Anne miscarried, her husband caught smallpox, and their two young daughters died of the same infection. Lady Rachel Russell wrote that George and Anne had "taken [the deaths] very heavily … Sometimes they wept, sometimes they mourned in words; then sat silent, hand in hand; he sick in bed, and she the carefullest nurse to him that can be imagined." Later that year, she suffered another stillbirth.”
>> I don’t know how I should consider the death of Anne’s 2 daughters. Did they truly die from smallpox? Regardless, so far, she had 3 stillborn children. Another indication of the McLeod Syndrome.
“Public alarm at James's Catholicism increased when his wife, Mary of Modena, became pregnant for the first time since James's accession. […]Anne suffered another miscarriage in April 1688, and left London to recuperate in the spa town of Bath.”
>> Miscarriage/stillborn number 4.
“Glorious Revolution
[…]On 24 July 1689, Anne gave birth to a son, Prince William, Duke of Gloucester, who, though ill, survived infancy. As King William and Queen Mary had no children, it looked as though Anne's son would eventually inherit the Crown.
William and Mary
[…] In April, Anne gave birth to a son who died within minutes. Mary visited her, but instead of offering comfort took the opportunity to berate Anne once again for her friendship with Sarah. The sisters never saw each other again. Later that year, Anne moved to Berkeley House in Piccadilly, London, where she had a stillborn daughter in March 1693.
[…]”
>> I hope I haven’t lost count = so far 6 lost children, right?
“Act of Settlement
Anne's final pregnancy ended on 25 January 1700 with a stillbirth. She had been pregnant at least seventeen times over as many years, and had miscarried or given birth to stillborn children at least twelve times. Of her five liveborn children, four died before reaching the age of two. Anne suffered from bouts of "gout" (pains in her limbs and eventually stomach and head) from at least 1698. Based on her foetal losses and physical symptoms, she may have had systemic lupus erythematosus, or antiphospholipid syndrome. Alternatively, pelvic inflammatory disease could explain why the onset of her symptoms roughly coincided with her penultimate pregnancy. Other suggested causes of her failed pregnancies are listeriosis, diabetes, intrauterine growth retardation, and rhesus incompatibility. Rhesus incompatibility, however, generally worsens with successive pregnancies, and so does not fit with the pattern of Anne's pregnancies, as her only son to survive infancy, Prince William, Duke of Gloucester, was born after a series of stillbirths. Experts also believe syphilis, porphyria and pelvic deformation to be unlikely as the symptoms are incompatible with her medical history.”
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