How can a naturally occurring amino acid be banned by the FDA and labeled as a drug?Because its effective against Covid 19 and FDA & Pharma doesnt like this natural cure!

WedMd article, not posting the link

Overview

N-acetyl cysteine (NAC) comes from the amino acid L-cysteine. Amino acids are building blocks of proteins. NAC has many uses and is an FDA approved drug.

N-acetyl cysteine is an antioxidant that might play a role in preventing cancer. As a drug, it's used by healthcare providers to treat acetaminophen (Tylenol) poisoning. It works by binding the poisonous forms of acetaminophen that are formed in the liver.

People commonly use N-acetyl cysteine for cough and other lung conditions. It is also used for flu, dry eye, and many other conditions, but there is no good scientific evidence to support many of these uses. There is also no good evidence to support using N-acetyl cysteine for COVID-19.

Although many dietary supplement products contain N-acetyl cysteine, the US FDA states that it's illegal for dietary supplements to contain N-acetyl cysteine since it's technically an approved drug. Prescription N-acetyl cysteine products are available under the guidance of a healthcare provider.

Effective

Complete or partial lung collapse(atelectasis). Inhaling a prescription form of N-acetyl cysteine helps treat collapsed lungs caused by mucus blockage. Prescription products must be given by a healthcare provider.

Lung tests. Inhaling a prescription form of N-acetyl cysteine is helpful to prepare people for diagnostic lung tests. Prescription products must be given by a healthcare provider.

Care of people with a tube placed in their windpipe(tracheostomy care). Inhaling a prescription form of N-acetyl cysteine helps prevent crusting in people with a tube in the windpipe. Prescription products must be given by a healthcare provider.

Possibly Effective for

Chest pain (angina). Taking N-acetyl cysteine by mouth or by IV seems to improve chest pain when used with the drug nitroglycerin. Taking N-acetyl cysteine by IV also seems to helpprevent nitroglycerin tolerance, but it might increase the risk for headaches and low blood pressure. IV products can only be given by a healthcare provider.

Autism. Taking N-acetyl cysteine by mouth might improve irritability in children and adolescents with autism. But it doesn't seem to help other autism symptoms.

Swelling (inflammation) of the main airways in the lung (bronchitis). Taking N-acetyl cysteine by mouth seems to reduce shortness of breath and coughing from this condition. Also, taking N-acetyl cysteine by mouth for 3-36 months seems to prevent flare-ups.

A lung disease that makes it harder to breathe (chronic obstructive pulmonary disease or COPD). Taking N-acetyl cysteine by mouth for at least 6 months seems to decrease flare-ups by about 40% in people with moderate to severe COPD. It seems to work best in people who are not already taking corticosteroids. In people with COPD who need to be hospitalized, taking N-acetyl cysteine in addition to regular treatment helps with recovery.

Kidney damagecaused by contrast dyes (contrast induced. But it only seems to help in people who already have poor kidney function.

High levels of homocysteine

Pubmed article (100s of studies of effectiveness)

The Potential Mechanism of N-acetylcysteine in Treating COVID-19

Nan Zhou et al. Curr Pharm Biotechnol. 2021.

N-Acetylcysteine (NAC) has been proposed to be used to treat Coronavirus Disease 2019 (COVID-19). By reviewing the existing pathological studies of COVID-19, it was found that abundant mucus secretion, formation of a hyaline membrane (supportive of acute respiratory distress syndrome), and interstitial fibrous exudation may be important characteristics of COVID-19 and pathological targets of drug therapy. In addition, multiple extrapulmonary organ injuries in COVID- 19 may be associated withcytokine storm. NAC is an important antioxidant and anti-inflammatory drug. NAC has been demonstrated to have mucolytic effects in bronchitis, relieve respiratory failure in acute respiratory distress syndrome, and inhibit fibrous exudation in interstitial lung disease in clinical studies. These findings suggest that NAC may have a therapeutic effect on the pathological targets of COVID-19. Furthermore, NAC decreases TNF-α, IL-1β, IL-6, IL-8, IL-10, and IL-17 serum levels in patients with sepsis, severe burns, acute liver failure, or peritoneal dialysis and may also reduce cytokine storm in COVID-19. The antiviral effect of NAC on other respiratory viruses may also benefit COVID-19 patients. Summarizing the potential mechanisms of NAC in treating COVID-19 suggests that the role of NAC in COVID-19 treatment is worthy of further research.

https://pubmed.ncbi.nlm.nih.gov/33371832/

Tripartite Combination of Candidate Pandemic Mitigation Agents:Vitamin D, Quercetin, and Estradiol Manifest Properties of Medicinal Agents for Targeted Mitigation of the COVID-19Pandemic Defined by Genomics-Guided Tracing of SARS-CoV-2 Targets in Human Cells

Gennadi V Glinsky. Biomedicines. 2020.

Abstract

Genes required for SARS-CoV-2 entry into human cells, ACE2 and FURIN, were employed as baits to build genomic-guided molecular maps of upstream regulatory elements, their expression and functions in the human body, and pathophysiologically relevant cell types. Repressors and activators of the ACE2 and FURIN genes were identified based on the analyses of gene silencing and overexpression experiments as well as relevant transgenic mouse models. Panels of repressors (VDR; GATA5; SFTPC; HIF1a) and activators (HMGA2; INSIG1; RUNX1; HNF4a; JNK1/c-FOS) were then employed to identify existing drugs manifesting in their effects on gene expression signatures of potential coronavirus infection mitigation agents. Using this strategy, vitamin D and quercetin have been identified as putative 2019 coronavirus disease (COVID-19) mitigation agents.Quercetin has been identified as one of top-scoring candidate therapeutics in the supercomputer SUMMIT drug-docking screen and Gene Set Enrichment Analyses (GSEA)of expression profiling experiments (EPEs), indicating that highly structurally similar quercetin, luteolin, and eriodictyol could serve as scaffolds for the development of efficient inhibitors of SARS-CoV-2 infection. In agreement with this notion, quercetin alters the expression of 98 of 332 (30%) of human genes encoding protein targets of SARS-CoV-2, thus potentially interfering with functions of 23 of 27 (85%) of the SARS-CoV-2 viral proteins in human cells. Similarly, Vitamin D may interfere with functions of 19 of 27 (70%) of the SARS-CoV-2 proteins by altering expression of 84 of 332 (25%) of human genes encoding protein targets of SARS-CoV-2. Considering the potential effects of both quercetin and vitamin D, the inference could be made that functions of 25 of 27 (93%) of SARS-CoV-2 proteins in human cells may be altered. GSEA and EPEs identify multiple drugs, smoking, and many disease conditions that appear to act as putative coronavirus infection-promoting agents. Discordant patterns of testosterone versus estradiol impacts on SARS-CoV-2 targets suggest a plausible molecular explanation of the apparently higher male mortality during the coronavirus pandemic. Estradiol, in contrast with testosterone, affects the expression of the majority of human genes (203 of 332; 61%) encoding SARS-CoV-2 targets, thus potentially interfering with functions of 26 of 27 SARS-CoV-2 viral proteins. A hypothetical tripartite combination consisting of quercetin/vitamin D/estradiol may affect expression of 244 of 332 (73%) human genes encoding SARS-CoV-2 targets. Of major concern is the ACE2 and FURIN expression in many human cells and tissues, including immune cells, suggesting that SARS-CoV-2 may infect a broad range of cellular targets in the human body. Infection of immune cells may cause immunosuppression, long-term persistence of the virus, and spread of the virus to secondary targets. Present analyses and numerous observational studies indicate that age-associated vitamin D deficiency may contribute to the high mortality of older adults and the elderly. Immediate availability for targeted experimental and clinical interrogations of potential COVID-19 pandemic mitigation agents, namely vitamin D and quercetin, as well as of the highly selective (Ki, 600 pm) intrinsically specific FURIN inhibitor (a1-antitrypsin Portland (a1-PDX), is considered an encouraging factor. Observations reported in this contribution are intended to facilitate follow-up targeted experimental studies and, if warranted, randomized clinical trials to identify and validate therapeutically viable interventions to combat the COVID-19 pandemic. Specifically, gene expression profiles of vitamin D and quercetin activities and their established safety records as over-the-counter medicinal substances strongly argue that they may represent viable candidates for further considerations of their potential utility as COVID-19 pandemic mitigation agents. In line with the results of present analyses, a randomized interventional clinical trial evaluating effects of estradiol on severity of the coronavirus infection in COVID19+ and presumptive COVID19+ patients and two interventional randomized clinical trials evaluating effects of vitamin D on prevention and treatment of COVID-19 were listed on the ClinicalTrials.gov website.

https://pubmed.ncbi.nlm.nih.gov/32455629/

Bernie Sanders Opposes Nomination Of Biden’s FDA Pick

Henry Rodgers

December 14, 2021 5:56 PM ET

Independent Vermont Sen. Bernie Sanders announced Tuesday his opposition to President Joe Biden’s pick to lead the Food and Drug Administration over ties to the pharmaceutical industry.

Sanders made the announcement in a tweet, saying Biden’s nominee, Robert Califf, is not willing to stand up to the pharmaceutical industry. The Vermont senator also included a video of his remarks at a Senate Health, Education, Labor and Pensions Committee meeting, where he serves.

“We need leadership at the FDA that is finally willing to stand up to the greed and power of the pharmaceutical industry. In this critical moment, Dr. Califf is not the leader Americans need at the agency and I will oppose his nomination,” Sanders said in the tweet.

Califf served as the head of the FDA from February 2016 until the end of the Obama administration.

We need leadership at the FDA that is finally willing to stand up to the greed and power of the pharmaceutical industry. In this critical moment, Dr. Califf is not the leader Americans need at the agency and I will oppose his nomination. pic.twitter.com/5tWuAlil6j

West Virginia Democratic Sen. Joe Manchin also came out against Califf’s nomination in November over his ties to the pharmaceutical industry. (RELATED: Manchin Opposes Biden’s FDA Nominee Over Pharmaceutical Ties)

“Dr. Califf’s nomination and his significant ties to the pharmaceutical industry take us backwards not forward,” Manchin said in a statement. “His nomination is an insult to the many families and individuals who have had their lives changed forever as a result of addiction.”

The FDA has been led by Acting Commissioner Dr. Janet Woodcock.

https://dailycaller.com/2021/12/14/bernie-sanders-opposes-nomination-joe-biden-fda-food-drug-administration-pharmaceutical-industry/

Smear Date Coming

White House Planning Event To Commemorate Jan. 6 Anniversary, Psaki Says

Anders Hagstrom

December 14, 2021 5:42 PM ET

White House press secretary Jen Psaki. (Screenshot/Youtube/Washington Post)

Washington Post/ Screenshot/ Youtube

The White House plans to hold an event commemorating the one-year anniversary of the pro-Trump storming of the U.S. Capitol on Jan. 6, White House press secretary Jen Psaki confirmed Tuesday.

Psaki made the statement during Tuesday’s White House press briefing, less than a month ahead of the anniversary of Jan. 6. President Joe Biden has repeatedly called the attack one of the “darkest days” in history for American democracy. (RELATED: Psaki Blames Republicans For Going Against Build Beck Batter Plan When Asked About Manchin, High Inflation)

“What does the White House plan to do, if anything, to commemorate Jan. 6? I feel like there’s been a little push an pull internally at the White House — You’re not necessarily wanting to elevate former President Donald Trump, but also wanting to respond to some of the threats, so how are you all approaching that?” a reporter asked.

“I don’t have anything to report to you at this point in time about our plans,” Psaki said. “I expect we will have more as we get closer to the end of the year, but to the president, January 6th was one of the darkest days in our democracy. It was a day that our nation’s Capitol was under attack, and I think there’s no question you’ll see us commemorate that day.”

https://dailycaller.com/2021/12/14/paski-january-6-anniversary-biden-white-house/

https://twitter.com/ScottAdamsSays/status/1470737245321658368?s=20

https://twitter.com/MZHemingway/status/1470889293384138755?s=20

Not Impressive but ElectionFraud is the word I’d use

Notable & Quotable: Elections

‘The fact that Trump won all but one of these bellwether counties again, despite losing nationally, is impressive.’

Dec. 13, 2021 6:27 pm ET

Much has been made of the fact that [Donald] Trump won 18 of the 19 bellwether counties in 2020 that had always voted with the national winner across the ten elections from 1980 to 2016. This stat is true but is less revealing than is often suggested. A more telling review of Trump’s performance in bellwether counties would rewind the clock to 2016. Prior to that election, there were 35 counties that had backed the national winner in every election from 1980 to 2012. In 2016, Trump won only 19 of these 35, breaking the streaks of 46% of them. The 18 that he won again in 2020, therefore, were somewhat self-selecting; they had already backed Trump once while many other bellwether counties hadn’t.

Still, the fact that Trump won all but one of these bellwether counties again, despite losing nationally, is impressive. Also impressive is that he won back two of the bellwether counties that he’d lost in 2016. The nature of those two reclaimed counties is revealing. One, Alamosa County, in south-central Colorado, is nearly half (48%) Hispanic. The other, Val Verde County in Texas, is on the Mexican border and went from backing Hillary Clinton by 8 points in 2016 to backing Trump by 10 points in 2020—an 18-point swing. Val Verde County is 82% Hispanic.

https://www.wsj.com/articles/notable-quotable-elections-bellwether-counties-vote-hispanic-latino-2020-presidential-race-2022-11639433895?st=0xl3e4pyxiolh0w&reflink=desktopwebshare_twitter

Another Clown Might! Kek

https://twitter.com/yesisworld/status/1470992145037340673?s=20