>>15267328

>THE ZINC PROPELS THE QUININE

Gentle correction required, Anon. Zinc is essential in this context. Getting it there is the job of the ionophore.

ionophore

NOUN

biochemistry

a substance which is able to transport particular ions across a lipid membrane in a cell.

Quercetin

Quercetin acts as a zinc ionophore (PubMed 2014), the same mechanism of action that hydroxychloroquine has via helping zinc pass the cell wall where it might halt viral replication. This zinc ionophore activity of quercetin facilitates the transport of zinc across the cell membrane.

Zinc ionophore activity of quercetin …

Dietary plant polyphenols such as the flavonoids quercetin (QCT) and epigallocatechin-gallate act as antioxidants and as signaling molecules. Remarkably, the activities of numerous enzymes that are targeted by polyphenols are dependent on zinc. We have previously shown that these polyphenols chelate zinc cations and hypothesized that these flavonoids might be also acting as zinc ionophores, transporting zinc cations through the plasma membrane. To prove this hypothesis, herein, we have demonstrated the capacity of QCT and epigallocatechin-gallate to rapidly increase labile zinc in mouse hepatocarcinoma Hepa 1-6 cells as well as, for the first time, in liposomes. In order to confirm that the polyphenols transport zinc cations across the plasma membrane independently of plasma membrane zinc transporters, QCT, epigallocatechin-gallate, or clioquinol (CQ), alone and combined with zinc, were added to unilamellar dipalmitoylphosphocholine/cholesterol liposomes loaded with membrane-impermeant FluoZin-3. Only the combinations of the chelators with zinc triggered a rapid increase of FluoZin-3 fluorescence within the liposomes, thus demonstrating the ionophore action of QCT, epigallocatechin-gallate, and CQ on lipid membrane systems.

https://pubmed.ncbi.nlm.nih.gov/25050823/

>>15267373

Thank you for doing so. I am also assisting to educate anons and contributing to the board. We are not at odds.

>>15267523

After burning half of New England's towns and killing 1/10 of the military-aged men in the colonies Metacom went into winter quarters at Schaghticoke, NY in December of 1675. He went there to enlist the help of the Iroquois Confederacy. Together they could have seriously hampered the ability of Europeans to maintain the colonies. Instead, they fought each other.

The issue has always been tribalism. We even do that today when we fight over sports teams, MAGA hats, or politics.

>>15267533

I have a friend and mentor seriously ill with sudden-onset liver dysfunction and diabetes post vaccination. He's scheduled for liver biopsy (LB). I sent these to him this morning:

https://www.ncbi.nlm.nih.gov/books/NBK570468/

The autoimmune hepatitis that has been described after COVID-19 vaccination has been linked to both mRNA and adenovirus based vaccines. It is unclear whether the autoimmune hepatitis is triggered by the vaccine or is a coincidental occurrence.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372667/

Although it is rare with vaccination, the COVID-19 vaccine is likely the cause of hepatotoxicity in our patient based on a diagnosis of exclusion. In this case, the patient had a cholestatic pattern with elevated ALP and bilirubin with mild elevation in the transaminases.

https://casereports.bmj.com/content/14/7/e242678

Although not proven, the temporal relationship of her vaccination with thrombocytopenia and abnormal liver enzymes points towards the Moderna mRNA-1273 SARS-CoV-2 vaccine as the most likely inciting factor.

https://www.sciencedirect.com/science/article/pii/S2213007121002306

We describe a case of sever hepatic artery thromboembolism presenting by acute liver failure associate with thrombocytopenia that occurred few days after ChAdOx1 nCov-19 vaccination for Covid-19 for the first time.

https://aasldpubs.onlinelibrary.wiley.com/doi/10.1002/hep.32156

Because anti-SARs-Cov-2 vaccination might rarely cause transaminasemia,[3, 4] drug-induced liver injury was a possible diagnosis in our patient, so LB was performed 6 months after vaccination due to persisting transaminasemia. This 6-month period coupled with the high serum IgG levels and the absence of recent use of hepatotoxic drugs and granulomas in LB make vaccine-induced AIH a probable diagnosis.

https://onlinelibrary.wiley.com/doi/10.1111/dme.14631

Acute hyperglycaemic crisis after vaccination against COVID-19: A case series

We describe three cases of acute hyperglycaemic crisis 3–5 weeks following first administration of an adenovirus-vectored COVID-19 vaccine presenting to a single hospital site within 1 week.

https://academic.oup.com/jes/article/5/11/bvab141/6375389

>>15267702

I'm not a lawfag, Anon, but I'll try. What happens is that citizens get complacent and do not pay much attention to school committee meetings, meetings of selectmen, public hearings, zoning board meetings, the various by-laws, ordinances, committee meetings, and mechanisms by which local, county, state, and federal rules, laws, and policies are proposed and accepted. They are then taken by surprise and say: 'How can they do this?' I'm not being critical. This is just my observation.

>>15267817

We are almost all disengaged. [They] know that. It's a stock answer to say: 'We had a meeting and you weren't there'. Our bylaws were decided in a meeting, too. We held a vote. You weren't there. The bylaws say we have to publish a notice in the newspaper. You don't get the paper? You should have said so at the meeting. Many local and county rules are 1950s era. Our complacency gets exploited.