Anonymous ID: 9da32a Jan. 13, 2022, 6:14 a.m. No.15364456   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>4474 >>4475

>>15364400

found something very fucking interesting from a quick frankincense ionophore search

FRANKINCENSEis a fucking ionophore

what gifts did the 3 wise men present to Jesus?

one was frankincense

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017322/

Triterpene Acids fromFrankincenseand Semi-Synthetic Derivatives That Inhibit 5-Lipoxygenase and Cathepsin G

Abstract

Age-related diseases, such as osteoarthritis, Alzheimerโ€™s disease, diabetes, and cardiovascular disease, are often associated with chronic unresolved inflammation. Neutrophils play central roles in this process by releasing tissue-degenerative proteases, such as cathepsin G, as well as pro-inflammatory leukotrienes produced by the 5-lipoxygenase (5-LO) pathway. Boswellic acids (BAs) are pentacyclic triterpene acids contained in the gum resin of the anti-inflammatory remedy frankincense that target cathepsin G and 5-LO in neutrophils, and might thus represent suitable leads for intervention with age-associated diseases that have a chronic inflammatory component. Here, we investigated whether, in addition to BAs, other triterpene acids from frankincense interfere with 5-LO and cathepsin G. We provide a comprehensive analysis of 17 natural tetra- or pentacyclic triterpene acids for suppression of 5-LO product synthesis in human neutrophils. These triterpene acids were also investigated for their direct interference with 5-LO and cathepsin G in cell-free assays. Furthermore, our studies were expanded to 10 semi-synthetic BA derivatives. Our data reveal that besides BAs, several tetra- and pentacyclic triterpene acids are effective or even superior inhibitors of 5-LO product formation in human neutrophils, and in parallel, inhibit cathepsin G. Their beneficial target profile may qualify triterpene acids as anti-inflammatory natural products and pharmacological leads for intervention with diseases related to aging.

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256410/

Potential therapeutic effects of boswellic acids and B. serrata extract against SARS-CoV-2-induced immune dysregulation

Autoimmune diseases are characterized by an uncontrolled overwhelming immune system reaction with enhanced T cell proliferation. B. serrata extracts and their active ingredients including boswellic acids affect the immune system in different ways (Table โ€‹(Table1).1). Boswellic acids have two different actions on cellular defense: they promoted lymphocyte proliferation in small doses while higher concentrations are inhibitory. In terms of the humoral defense system, boswellic acids also reduced primary antibody titers at higher doses; however, lower doses increased secondary antibody titers. Moreover,boswellic acids enhance the phagocytosis of macrophages(Mikhaeil et al. 2003; Pungle et al. 2003; Ammon 2011; Siddiqui 2011). Beghelli et al. (2017) suggested that B. serrata has a promising potential to modulate not only inflammation/oxidative stress but also immune dysregulation.

 

dig here amigos

Anonymous ID: 9da32a Jan. 13, 2022, 6:21 a.m. No.15364487   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>4668

>>15364475

we love phagocytosis of macophages in advanced cancer curing as practices by anons

it's like the russian said on Cosmic mildew about the macrophages and how important they are

but then them not undergoing apoptosis quick enough was killing people during the bioweapon induced cytokine storms

this looks like it solves that