>Queen of Canada
wrong room.
royals and slaves define each other.
The Washington Post
Experimental HIV vaccine, based on Moderna’s mRNA technology, now in clinical trial
Ellen Francis - Tuesday
https://www.msn.com/en-us/health/medical/experimental-hiv-vaccine-based-on-moderna-s-mrna-technology-now-in-clinical-trial/ar-AATmSym
Researchers have started administering doses of an experimental HIV vaccine that uses the breakthrough mRNA technology in Moderna’s coronavirus shot.
U.S. biotech firm Moderna and the nonprofit International Aids Vaccine Initiative (IAVI) are exploring the use of mRNA technology, which prompts the body to make a protein that triggers an immune response (the technology also is used in Pfizer’s coronavirus shot). Researchers will monitor 56 HIV-negative adults for six months in the Phase 1 clinical trial, typically the first step in a long road to study the safety and efficacy of a vaccine.
George Washington University, one of the sites where the trial is taking place, described it as the first human trial of a mRNA-based HIV vaccine.
Nearly four decades of research and advocacy have produced medications that transformed HIV into a manageable virus, although there still is no vaccine to help prevent hundreds of thousands of deaths a year. Dozens of attempts have been abandoned before preclinical or clinical stages of evaluation, but the HIV research helped hone technologies that were repurposed against covid-19.
Decades of research on an HIV vaccine boost the bid for one against coronavirus
The coronavirus pandemic has marshaled global resources, and billions of dollars from governments and private companies, into research into coronavirus vaccines, which were fast-tracked and developed in record time.
Scientists have sought to harness that momentum in the long-standing battle against other threats. In October, the World Health Organization endorsed the world’s first malaria vaccine for use in children — production of that vaccine was slowed by the difficulty of targeting a parasite and securing funding to prevent a disease most destructive in poorer parts of the world.
WHO endorses use of first malaria vaccine
Last year, a broad study that had raised hopes of a vaccine for HIV ended in failure after an interim analysis showed it was no more effective than a placebo. It was the seventh full-scale human trial of a vaccine for HIV, which newly infected 1.5 million people worldwide in 2020, according to U.N. data.
HIV integrates itself into the body’s cells, meaning a vaccine has to start working immediately to rout it.
The new trial in the United States, which Moderna announced began on Thursday, will test a hypothesis that delivering HIV immunogens — proteins that elicit an immune response to HIV — through mRNA technology can spur the body to produce antibodies that neutralize a range of HIV variants.
This “is widely considered to be a goal of HIV vaccination, and this is the first step in that process,” the company said in a statement. Forty-eight participants will get one or two doses of the vaccine, with 32 of them also taking a booster shot. The other eight volunteers will receive only the booster.
“The search for an HIV vaccine has been long and challenging, Mark Feinberg, the president of IAVI, said in a statement. “Having new tools in terms of immunogens and platforms could be the key to making rapid progress toward an urgently needed, effective HIV vaccine.”
>Experimental HIV vaccine, based on Moderna’s mRNA technology
perfect timing, eh?
https://www.dailymail.co.uk/health/article-10473495/New-HIV-strain-Netherlands-Highly-infectious-variant-makes-people-ill-twice-quick.html
New HIV super-strain is found in the Netherlands: Highly infectious variant makes people ill twice as quickly and has been spotted in at least 109 people
-VB variant has infected 109 people, the majority of whom are in the Netherlands
-The strain damages the immune system twice as fast as other variants of virus
-Treatment leads to survival rate similar to those infected with other strains
By EMILY CRAIG HEALTH REPORTER FOR MAILONLINE
PUBLISHED: 14:00 EST, 3 February 2022 | UPDATED: 05:36 EST, 4 February 2022
A new super-mutant HIV strain that makes infected individuals ill twice as fast as current versions of the virus has been detected in the Netherlands.
The new mutant — called the VB variant — has infected at least 109 people, according to a study by Oxford University.
The strain damages the immune system and weakens a person's ability to fight everyday infections and disease faster than previous versions of the virus.
It means those who catch this strain could develop AIDS more quickly.
The VB variant also has a viral load between 3.5 and 5.5 times higher than the current strain, meaning infected people are more likely to transmit the virus to others.
However, after starting treatment, those with the variant have a similar immune system recovery and survival rate to those infected with other HIV strains.
But the researchers warned the rapid health decline after catching VB means early detection and treatment is 'critical'.
Britons are advised to get tested for HIV and other STIs at least one a year, while men who have sex with men are advised to get tested every three months.
More than 100,000 Britons and 1million Americans are thought to be living with HIV.
Independent experts have said the finding is nothing to panic about. The analysis found VB arose in the 1980s and has been declining since 2010.
An analysis of genetic patterns suggests VB first arose during the late 1980s and 1990s in the Netherlands.
The discovery, published in the journal Science, is the result of an international collaboration between the University of Oxford's Big Data Institute and the Dutch HIV Monitoring Foundation.
The team, which collects HIV samples from across Europe and Uganda, detected 17 cases of the new strain.
Just like Covid, HIV mutates very quickly but the vast majority of these changes make no difference to the nature of the virus.
Two of the cases were in Switzerland and Belgium, while 15 VB variant samples were taken from individuals in the Netherlands.
The team examined positive samples from more than 6,700 people in the country to find out how widespread it ix.
This process identified a further 92 people with the variant, from all regions of the Netherlands, bringing the total of confirmed cases to 109. But the true number is likely to be higher.
The team examined sequenced HIV samples from a global database but did not detect other cases. However, they said there are 'probably at least a few' more international cases of the strain.
By analysing genetic variation among the samples, the team estimated that the VB variant first emerged in the late 1980 or 1990s in the Netherlands.
They found it spread faster than other strains during the 2000s before declining since 2010 in response to treatment becoming widely available.
It is unclear how the variant emerged, but the team said one option could be an unusually long infection in one person who did not undergo treatment to stop the virus from replicating and evolving.
The scientists do not yet know how the variant is more transmissible and damaging to the immune system.
pt1
People infected with the strain had the same characteristics — including age and sex — as other people living with HIV in the Netherlands, the researchers noted.
The experts said further studies into the variant's mechanisms could reveal new parts of the virus to target through drugs.
Dr Chris Wymant, a senior researcher in statistical genetics at Oxford University and lead author, said: 'Before this study, the genetics of the HIV virus were known to be relevant for virulence, implying that the evolution of a new variant could change its impact on health.
'Discovery of the VB variant demonstrated this, providing a rare example of the risk posed by viral virulence evolution.'
Professor Christophe Fraser, an expert in pathogen dynamics at the university and study senior author, said: 'Our findings emphasise the importance of World Health Organization guidance that individuals at risk of acquiring HIV have access to regular testing to allow early diagnosis, followed by immediate treatment.
'This limits the amount of time HIV can damage an individual's immune system and jeopardise their health.
'It also ensures that HIV is suppressed as quickly as possible, which prevents transmission to other individuals.'
pt 2 of 2
>What are they planning now
Next up? Perhaps Nano-SaaS Immune System by Pfizer/Moderna/ Verizon/ATT etc
Software as a Service
You can pay for an update/vaxx to allow for some level of immune system functionality.
If not, the millimeter waves and the nanolipid metals will kill you shortly…
he is a magician. he can make hiv dissapear.
>Treasury urges closer watch on money laundering in
Real Estate, commercial AND residential? silence
Construction? silence
NPO/NGOs? silence
No bid contracts, nepotism, masonic and other backdoor, oath driven deals? silence
higher education? silence
film production? silence
religious organizations? silence
Treasury, IRS, DHS, FBI, and DOJ etc do not GAF about exposing the Global Human Livestock Plantation that they manage, obfuscate, and PROFIT FROM.
when will the world learn that baby farms, planned parenthoods, red crosses, etc are FOOD/DRUG suppliers for FIENDS? The bite with no cure.
"Lillian Hannity (Flynn) is an American celebrity mother widely known for being the mother of Sean Hannity. Lillian F. Hannity Age Lillian Flynn was 69 years of age when she passed away. She was born on April 09, 1931, in New York, New York, United States. She died on March 24, 2001 (aged 69) inBroward County, Florida, United States."