The MRC-5 cell line was developed in September 1966 from lung tissue taken from
a 14 week fetus aborted for psychiatric reason from a 27 year old physically
healthy woman. The cell morphology is fibroblast-like. The karyotype is 46,XY;
normal diploid male. Cumulative population doublings to senescence is 42-48.
G6PD isoenzyme is type B.
https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf
https://www.vaccinesafety.edu/components-Excipients.htm
Use of Aborted Fetal Tissue in Vaccines and Medical Research Obscures the Value of All Human Life
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027112/
Vaccines currently in use in the United States contain ingredients including
“human fetus cells lines” and “African Green Monkey kidney pus cells” harvested
from diseased primates, according to a bombshell document published by the
CDC. The report also shows that other substances are used in vaccines
manufactured for human use, including: porcine circoviruses, Thimerosal,
aluminum, formaldehyde, human serum albumin, diploid human cell, human
embryonic kidney cells 293, also often referred to as HEK 293, HEK-293, 293
cells, or less precisely as HEK cells, human fetal cells listed as WI-38, MRC-5,
HEK293, and more. — Editor
https://uowiscorg.files.wordpress.com/2021/08/aborted-cells.pdf
Characteristics and viral propagation properties of a new human diploid cell line, Walvax-2, and its suitability as a candidate cell substrate for vaccine production
https://pubmed.ncbi.nlm.nih.gov/25803132/
Why are human foetal cell lines being used in research? One major approach to developing a new vaccine for corona virus is to use viral vectors, such as adenovirus. Johnson and Johnson in the USA and the University of Oxford (partnered with the pharmaceutical company AstraZeneca) have used adenovirus approaches. These require the use of cell lines such as the HEK (human embryonic kidney) 293 cell-line, which is derived from tissues of a foetus aborted in 1972 (Wadman, 2020b).
HEK293 cell lines enable the deletion of genes so that the adenovirus vector does not replicate in the vaccinee’s cells (He et al., 1998; Thomas and Smart, 2005). Thus, the virus contains the gene which stimulates production of COVID-19 proteins, which elicit immunity, without overwhelming cells with the virus, which can happen with natural infection. In other words, HEK293 cell lines make vaccine development efficient, because they contain the genetic material necessary to produce the desired adenoviruses and that cannot be obtained through animal cell lines, and safe, because the resulting adenovirus would not contain the genes that would replicate the virus and infect the cells of the vaccinees.
The Pfizer/BioNTech vaccine does not use foetal cell lines in the development of the vaccine, although it did use it to test the vaccine. For those who object to research linked to abortion, it might not be ‘ethically uncontroversial’, as some have called it (e.g. Sherley and Prentice, 2020), but to many, it is less controversial than, for example, the Oxford/AstraZeneca vaccine. It might be objected that this makes it unnecessary to use vaccines using an adenovirus. But this would be a mistake. We need as many different vaccines as possible. Besides, there are serious drawbacks with an mRNA vaccine. It must be stored at −70°C (−94 F) and it can’t be removed from the fridge more than four times.1 This severely limits its distribution, especially considering that it must be administered in two doses. Many countries have already invested and signed agreements for the production of adenovirus vaccines. For quite some time, there will be vaccine shortages and because in a pandemic time is lives, changing vaccine may cost significant numbers of lives. The more vaccines are approved, the more availability we will have in the shorter term, and the more lives will be preserved.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344725/
Just thought it was interesting.
Which ones do and do not use the lines in production, presumably.
I do not support this.