how does ivermectin work on the effects of a snake bite? plz help
-Cobratoxin at Concentrations of Up to 40 M Does Not Inhibit Homopentameric Glycine Receptor—Glycine receptor is another example of abundantly expressed Cl-permeable Cys-
loop receptors. It also shares very high sequence homology with GABA AR subunits. To check whether -Ctx possesses some
activity against this receptor, we tested its activity against the human homopentameric
1 glycine receptor. At concentra-
tions up to 40 M , -Ctx failed to inhibit glycine-evoked currents (data not shown). Thus, -Ctx blocks GABA ARs but not
the glycine receptor.
However, it should be noticed that there are other subsets of glycine receptor that were not tested.
>https://www.jbc.org/article/S0021-9258(20)44829-X/pdf
is this why ivermectin also works thus venom theory holds?
'Oh9-1 (King Cobra venom) increase the effect of the human glycine receptor with 2 fold activity increase'
>https://www.wjgnet.com/1949-8454/full/v10/i1/17.htm
this study is from Russia
all i need is pipe tobacco and ivermectin.
glow less please
>https://www.aaas.org/news/aaas-member-satoshi-omura-awarded-2015-nobel-prize-physiology-or-medicine