>>16203038
>Diseases of Civilization: Are Seed Oil Excesses the Unifying Mechanism?'
How Seed Oils Destroy Your Mitochondria and Lead To Chronic Disease, with Tucker Goodrich
https://carnivoremd.com/how-seed-oils-destroy-your-mitochondria-and-lead-to-chronic-disease-with-tucker-goodrich/
0:09:38 0:03:21 Podcast Begins
0:11:12 0:04:55 What is Linoleic Acid?
0:16:44 0:10:27 How Linoleic acid caused disease
0:21:06 0:14:49 Understanding cardiolipin and the electron transport chain
0:23:28 0:17:11 Linoleic acid drives mitochondrial dysfunction, causes chronic illness
0:26:41 0:20:24 Maintenance of Cardiolipin and Crista Structure Requires Cooperative Functions of Mitochondrial Dynamics and Phospholipid Transport https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026740/
0:32:56 0:26:39 Linoleic acid is uniquely damaging
0:35:30 0:29:13 Myths surrounding linoleic acid
0:38:19 0:32:02 The supremacy of animal fats
0:41:05 0:34:48 Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA https://journals.physiology.org/doi/full/10.1152/ajpheart.00480.2004?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org
0:42:25 0:36:08 How seed oil consumption leads to necrosis and CVD
0:49:38 0:43:21 Mainstream understanding of PUFAs is built on faulty epidemiology
0:56:21 0:50:04 Circulating levels of linoleic acid and HDL-cholesterol are major determinants of 4-hydroxynonenal protein adducts in patients with heart failurehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909262/
0:58:49 0:52:32 All about OxLAMs
1:03:32 0:57:15 Oxidized omega-6s are essential for atherosclerosis
1:13:33 1:07:16 Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467319/
1:14:30 1:08:13 Strong increase in hydroxy fatty acids derived from linoleic acid in human low density lipoproteins of atherosclerotic patients https://www.sciencedirect.com/science/article/abs/pii/S0009308497000959?via%3Dihub
1:15:38 1:09:21 The root cause of oxidative stress is linoleic acid
1:18:17 1:12:00 Metabolites of arachidonic acid and linoleic acid in early stages of non-alcoholic fatty liver disease—A pilot study https://www.sciencedirect.com/science/article/abs/pii/S1098882315300101
1:19:56 1:13:39 How Linoleic acid affects immunity
1:44:03 1:37:46 The linoleic acid-chronic illness hypothesis is air-tight
1:48:14 1:41:57 Calories In, Calories Out is the wrong paradigm
1:51:01 1:44:44 Role of Physiological Levels of 4-Hydroxynonenal on Adipocyte Biology: Implications for Obesity and Metabolic Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038367/
1:51:53 1:45:36 Eating seed oils is about as smart as eating poison ivy
1:54:54 1:48:37 Tucker Goodrich radical paleo evangelism
1:58:19 1:52:02 Where to find Tucker Goodrich