dChan
Anonymous ID: 206d84 May 14, 2022, 6:10 p.m. No.16276336   🗄️.is 🔗kun   >>6339

Ukrainian officials plan to demolish the monument "Three Sisters" on the border of the Russian Federation, Belarus and Ukraine

 

Apparently, all other problems - supplying their militants with fuel and lubricants, restoring the railway infrastructure, revitalizing the economy, eliminating banditry after the uncontrolled distribution of weapons, raising the morale of their soldiers, eliminating the zrada with terrorists hiding under Azovstal, restoring the rights of the opposition and the media, stopping the export from the countries of essential goods and grain have already been decided. You can think about the damage to relations with neighbors.

 

https://gab.com/Vorontzov/posts/108291487448788634

Anonymous ID: 206d84 May 14, 2022, 6:13 p.m. No.16276358   🗄️.is 🔗kun   >>6640 >>6760

Long-Term Benzodiazepine (Xanax, Klonopin, Ativan) Use Destroys Neural Connections in the Brain

March 27, 2022

 

Long-Term Benzodiazepine Use Attacks Synapses

 

Long-term use of benzodiazepines has been linked to cognitive deficits according to Ludwig Maximilian University Of Munich (LMU) researchers.

 

Benzodiazepines are a class of medications that are used to treat anxiety and sleep disorders. While short-term treatments are typically safe, long-term use may develop into physical dependency and, in the case of the elderly, cognitive problems. Previously, the mechanisms by which benzodiazepines cause these alterations were unclear. Prof. Jochen Herms and Dr. Mario Dorostkar of LMU’s Center for Neuropathology and Prion Research and the German Center for Neurodegenerative Diseases (DZNE) have now shown that the active ingredient causes the breakdown of neural connections in the brain in an animal model.

 

Microglia, which are brain immune cells, play an important function. Benzodiazepines attach to a particular protein on the surface of microglia cell organelles called the translocator protein (TSPO). The microglia are activated as a result of this binding. This causes them to break down and recycle synapses, which are the connections between nerve cells. Experiments conducted by the researchers revealed that synapse loss in mice that were given a daily sleep-inducing dosage of the benzodiazepine diazepam for several weeks resulted in cognitive deficits.

 

“It was known that microglia play an important role in eliminating synapses both during brain development and in neurodegenerative diseases,” said Dr. Yuan Shi and Mochen Cui, co-authors of the study. “But what really surprised us was that such well-researched drugs as benzodiazepines influence this process.” When diazepam medication was stopped, the effects lingered for a while but were eventually reversed.

 

The findings, according to the researchers, could have an impact on how sleep difficulties and anxiety are managed in patients that could have dementia. The authors state “Drugs that are known to have no binding affinity to TSPO should be preferred where possible.”

 

Reference: “Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO)” by Yuan Shi, Mochen Cui, Katharina Ochs, Matthias Brendel, Felix L. Strübing, Nils Briel, Florian Eckenweber, Chengyu Zou, Richard B. Banati, Guo-Jun Liu, Ryan J. Middleton, Rainer Rupprecht, Uwe Rudolph, Hanns Ulrich Zeilhofer, Gerhard Rammes, Jochen Herms and Mario M. Dorostkar, 28 February 2022, Nature Neuroscience.

DOI: 10.1038/s41593-022-01013-9

 

https://scitechdaily.com/long-term-benzodiazepine-xanax-klonopin-ativan-use-destroys-neural-connections-in-the-brain/

Anonymous ID: 206d84 May 14, 2022, 6:18 p.m. No.16276393   🗄️.is 🔗kun   >>6640 >>6760 >>6782

Recognize Deep Narcissists before You Fall for Them:

 

You can recognize deep narcissists by the following behavior patterns: If they are ever insulted or challenged, they have no defense, nothing internal to soothe them or validate their worth.

 

They generally react with great rage, thirsting for vengeance, full of a sense of righteousness.

This is the only way they know how to assuage their insecurities. In such battles, they will position themselves as the wounded victim, confusing others and even drawing sympathy.

They are prickly and oversensitive.

 

Almost everything is taken personally.

 

They can become quite paranoid and have enemies in all directions to point to. You can see an impatient or distant look on their face whenever you talk about something that does not directly involve them in some way. They immediately turn the conversation back to themselves, with some story or anecdote to distract from the insecurity behind it.

They can be prone to vicious bouts of envy if they see others getting the attention they feel they deserve. They frequently display extreme self-confidence. This always helps to gain attention, and it neatly covers up their gaping inner emptiness and their fragmented sense of self. But “beware if this confidence is ever truly put to the test. When it comes to other people in their lives, deep narcissists have an unusual relationship that is hard for us to understand. They tend to see others as extensions of themselves, what is known as self-objects. People exist as instruments for attention and validation.

 

Their desire is to control them like they control their own arm or leg. In a relationship, they will slowly make the partner cut off contact with friends—there must be no competition for attention.

 

https://gab.com/Jonnie_AkA_SnakeDoc25/posts/108295915931647333