Experimental methods[edit]
The high degree of homology between D5 and D1 receptors and their affinity for drugs with similar pharmacological profile complicate distinguishing between them in research. Antibody staining these two receptors separately is suggested to be inefficient.[44] However, expression of D5 receptors has been assessed using immunohistochemistry. In this technique, two peptides were obtained from third exracellular loop and third intracellular loop of the receptor, and antisera were developed for staining the receptor in frozen mouse brain tissue.[35] A method involving mRNA probes for in situ hybridization has been developed, which allowed to separately examine the expression of D1 and D5 receptors in the mouse brain.[24]
DRD5 knockout mice can be obtained by crossing 129/SvJ1 and C57BL/6J mice.[10] D5 receptor can also be inactivated in an animal model by flanking the DRD5 gene with loxP site, allowing to generate tissue or animal lacking functional D5 receptors.[45] The expression of D5 receptor in vitro can also be silenced using antisense oligonucleotides.[20]
Dopamine receptor D5, also known as D1BR, is a protein that in humans is encoded by the DRD5 gene.[5] It belongs to the D1-like receptor family along with the D1 receptor subtype.
https://en.wikipedia.org/wiki/Dopamine_receptor_D5#Inverse_agonists
Random and purposeful
Christopher Covelli
Parents of little
Intentional and random, how do they know?
Why is that kid on his lap.
This is not how this works.
Stealing kids in plain sight now?
Famous people from Highland Park, Il
Aaron Swartz, pioneer in internet technology and activism for free digital culture[1]
Arts and entertainment[edit]
Craig Bolotin, screenwriter, film director
Alex Borstein, actress
Paul Brickman, film director[citation needed]
Rachel Brosnahan, actress
Patrick Burns, reality TV star (Haunting Evidence)
Jacqueline Carey, fantasy fiction novelist
Mickie Caspi, artist
Billy Corgan, lead singer and founder of the band Smashing Pumpkins
Blag Dahlia, singer in The Dwarves
Eric Engberg, broadcast journalist
Brenda Ferber, author
Jennie Fields, writer, author of Crossing Brooklyn Ferry, Lily Beach, and The Middle Ages
Brett Gelman, actor
Michael Gelman, producer, Live With Regis and Kelly
Stephen Glass, discredited magazine journalist[2]
James Goldman, screenwriter and playwright, author of The Lion in Winter
William Goldman, Academy Award-winning screenwriter, author of The Princess Bride
F. Gary Gray, film director
Chief Keef, rapper and producer
Brian Levant, film director
Donald Lipski, artist
Sebastian Maniscalco, comedian[citation needed]
Richard Marx, singer-songwriter, producer
Jeff Melvin, television writer and producer
Ken Olin, actor, director, producer
Peter Orner, author[citation needed]
Jeff Perry, actor
Cory Provus, baseball broadcaster
Robert Reed, actor
Ben Savage, actor
Fred Savage, actor and director
Kala Savage, actress and singer
Josh Server, actor
Robert Seyfarth, architect
Gary Sinise, actor
Grace Slick, of the band Jefferson Airplane, born in Highland Park
Harold Ramis, actor and director[citation needed]
Brandon Ratcliff, actor
Brian Ross, broadcast journalist[citation needed]
David Seltzer, screenwriter, producer, and director
Gene Siskel, film critic[citation needed]
George Kirke Spoor, film pioneer
Lauren Tom, actress
D.B. Weiss, co-creator of Game of Thrones TV series[3]
Orson Welles, actor and director
Edward Weston, photographer[4]
Dan Witz, artist
Dean Zelinsky, founder of Dean Guitars
Business[edit]
Anthony Saliba, (born 1955), author & businessman
Steve Sarowitz (born 1965/1966), American billionaire, founder of Paylocity[5]
Seems like a lot
https://en.wikipedia.org/wiki/List_of_people_from_Highland_Park,_Illinois
The reports also show that "Soylent Green" is being produced from the remains of the dead and the imprisoned, obtained from heavily guarded waste disposal plants outside the city. The Books further reveal that Simonson's murder was ordered by his fellow Soylent Corporation board members, who knew Simonson was increasingly troubled by the truth and feared he might disclose it to the public.
On hearing the truth, Roth is so shaken he decides to "return to the Home of God" andseeks assisted suicide at a government clinic
Everything
Soylent green turns to shit
Covid shots gov assisted suicide…feed to poor to the hungry
Same
Struggles
It sucks when you cant get away with murder
My guess…every nwo country has a death quota to meet. Maybe theyre playing a game of Great Race and placing high stakes bets on the contestants
False Flag ref based on alligator comms
They know it was intentional yet random without knowing motive
Does that head wound look right?
I like think RRN is the future that proves past
Did I hear the officer ask for phone videos to be brought in?
The moon is a but a reflection of a future and desolated Earth?
Shut up, mike
HIGHLAND PARK
Former Highland Park mayor dies from COVID-19 complications at age 91
By James T. Norman
Pioneer Press
•
May 08, 2020 at 10:42 am
https://www.chicagotribune.com/suburbs/highland-park/ct-hpn-former-mayor-dies-coronavirus-tl-0514-20200508-5swacugmm5cvdc4apelcxn4jya-story.html