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ADHD
What's missing?
ADHD
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702182/
Objective: The purpose of this study was to investigate the clinical effect and safety of a broad spectrum, 36 ingredient micronutrient (vitamins and minerals) in treating children with attention-deficit/hyperactivity disorder (ADHD).
Results: Modified Brinley plots revealed a reduction in ADHD symptoms, improved mood, and improved overall functioning during intervention phases, and deterioration in ADHD symptoms, mood, and overall functioning during the withdrawal phases. Reliable change analyses, Cohen's d and percent superiority effect sizes, 95% confidence intervals and t tests confirmed clinically and statistically significant change between the intervention and withdrawal phases, with large effect sizes observed pre- to post-exposure of micronutrients (d = 1.2–2.2) on ADHD symptoms during intervention phases. Seventy-one percent of participants showed at least a 30% decrease in ADHD symptoms by the end of the second treatment phase, and 79% were identified as “much improved” or “very much improved” at the end of the second phase (5 months) based on the clinician-rated CGI when considering functioning generally. The SDQ showed that these benefits occurred across other areas of functioning including emotional symptoms, conduct problems, and prosocial behaviours. The children's self-reports confirmed the improvements. Excellent adherence to treatment occurred throughout, side effects were mild and transitory, and no safety issues were identified through blood analyses.
Conclusions: This study demonstrates the clinical benefit, feasibility, and safety of broad-spectrum micronutrients in the treatment of childhood ADHD. Replications utilizing double-blind placebo-controlled studies are warranted. Trial is registered with the Australia and New Zealand Clinical Trial Registry: ACTRN12612000645853
Table 1.
EMPowerplus Capsule Ingredient List
1 capsule 4 capsules 8 capsules 15 capsules
Vitamin A 384.0 IM 1536.0 IM 3072.0 IM 5760 IM
Vitamin C 40.0 mg 160.0 mg 320.0 mg 600 mg
Vitamin D 96.0 IM 384.0 IM 768.0 IM 1440 IM
Vitamin E 24.0 IM 96.0 IM 192.0 IM 360 IM
Vitamin B1 1.2 mg 4.8 mg 9.6 mg 18 mg
Vitamin B2 0.9 mg 3.6 mg 7.2 mg 13.5 mg
Vitamin B3 6.0 mg 24.0 mg 48.0 mg 90 mg
Vitamin B5 1.4 mg 5.8 mg 11.5 mg 21.6 mg
Vitamin B6 2.4 mg 9.6 mg 19.2 mg ?36 mg
Vitamin B9 96.0 µg 384.0 µg 768.0 µg 1440 µg
Vitamin B12 60.0 µg 240.0 µg 480.0 µg 900 µg
Vitamin H 72.0 µg 288.0 µg 576.0 µg 1080 µg
Calcium 88.0 mg 352.0 mg 704.0 mg 1320 mg
Iron 0.9 mg 3.7 mg 7.3 mg 13.74 mg
Phosphorus 56.0 mg 224.0 mg 448.0 mg 840 mg
Iodine 13.6 µg 54.4 µg 108.8 µg 204 µg
Magnesium 40.0 mg 160.0 mg 320.0 mg 600 mg
Zinc 3.2 mg 12.8 mg 25.6 mg 48 mg
Selenium 13.6 µg 54.4 µg 108.8 µg 204 µg
Copper 0.5 mg 1.9 mg 3.8 mg 7.2 mg
Managnese 0.6 mg 2.6 mg 5.1 mg 9.6 mg
Chromium 41.6 µg 166.4 µg 332.8 µg 624 µg
Molybdenum 9.6 µg 38.4 µg 76.8 µg 144 µg
Potassium 16.0 mg 64.0 mg 128.0 mg 240 mg
Plus a proprietary blend of: dl-phenylalanine, glutamine, citrus bioflavanoids, grape seed, choline bitartrate, inositol, ginkgo biloba, methionine, germanium sesquioxide, boron, nickel, and vanadium.
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