dChan
Anonymous ID: c2a6e4 Oct. 4, 2022, 8:14 a.m. No.17630673   🗄️.is đź”—kun   >>0681

>>17630658

47,XXY female with testicular feminization and positive SRY: a case report

Eloisa Saavedra-Castillo 1 , Elva I Cortés-Gutiérrez, Martha I Dávila-Rodríguez, María Eugenia Reyes-Martínez, Amalia Oliveros-Rodríguez

Affiliations

 

PMID: 15755052

 

Abstract

 

Background: Males with a 47,XXY karyotype have the clinical phenotype of Klinefelter syndrome. A few 47,XXY cases with a female phenotype have been reported. These individuals have positive SRY (testis-determining factor). The genetic explanation of this phenomenon is unclear.

 

Case: A 34-year-old woman presented with testicular feminization and a 47,XXY karyotype. Cytogenetic analysis and fluorescence in situ hybridization suggested that the Y chromosome had a normal structure; the polymerase chain reaction was positive for SRY.

 

Conclusion: This is the third reported case of 47,XXY with afemale phenotype in spite of the presence of a Y chromosome and the normal SRY. This suggests that the phenotypic sex in these patients might be due to the involvement of other sex-determining genes.

 

https://pubmed.ncbi.nlm.nih.gov/15755052/

Anonymous ID: c2a6e4 Oct. 4, 2022, 8:41 a.m. No.17630790   🗄️.is đź”—kun   >>1017

>>17630767

 

Standing in the kitchen and acting out his role, Podesta explained: “It’s best to do the butchering at 4 a.m., “because pigs should be slaughtered when it is cool, and it takes a long time to roast them. The pig is hauled on a front-end loader in order to split and gut it. It’s most important to slow the pig down by shooting it between the eyes so you can cut its throat. It makes the pig less ornery and a whole lot more cooperative than if you just stick a knife in its throat.”

 

https://www.politico.com/story/2009/07/john-podesta-a-seasoned-hand-024575