That Great Whore.
Check the qualifiers. It ain't Rome; that's Jewish disinfo. Only Jerusalem is drunk with the blood of saints and prophets.
In Revelation, Jerusalem gets destroyed - that "fair city" "where our Lord was crucified."
Jesus wasn't crucified in Rome.
Jerusalem. The marriage of Islam and Judaism with antichrist sitting in the rebuilt temple and proclaiming himself god. Where? Not Rome. Jerusalem. The ultimate adultery.