Pfizer

Rezifp/ Resheph

The name Rezifp is of Hebrew origin and means "(Hebrew: 'the Burner' or 'the Ravager') ancient West Semitic god of the plague and of the underworld==, the companion of Anath, and the equivalent of the Babylonian god Nergal. He was also a war god and was thus represented as a bearded man brandishing an ax, holding a shield, and wearing a tall, pointed headdress with a goat's or gazelle's head on his forehead".

https://www.names.org/n/rezifp/about#associations

https://en.wikipedia.org/wiki/Resheph

Breaking: SARS-CoV-2 Spike found in bacteria samples taken from China, 2019

http://adeno-news.com/2023/01/20/breaking-sars-cov-2-spike-found-in-bacteria-samples-taken-from-china-2019/

Now there is more mystery regarding the history of SARS-CoV-2 before the pandemic in case of China.

Previously, SARS-CoV-2 genomic sequences corresponding to both A,B lineage as well as USA-WA-1 was found within samples of Antarctic soil that were extracted and sent for sequencing in December 2019, 101 runs prior to the first sequencing of samples taken from “viral pneumonia of unknown etiology” patients from the Huanan seafood market by the Wuhan Institute of Virology. It appeared that these samples were not the only samples that were taken from China in 2019, that contained sequences derived from SARS-CoV-2 and were decidedly NOT linked to the wildlife trade in any way.

Very recently, Twitter user @MartinaSisters have discovered that the SARS-CoV-2 Spike protein is present within Bacterial whole-genome sequencing assembly data, deposited under PRJNA839565, that supposedly contained sequences taken from isolated samples of Pseudomonas Aeruginosa that were taken from patients in 2019, Henan.

More specifically, the SARS-CoV-2 Spike protein have been found within the following 4 WGS shotgun contig sequences, each corresponding to a cultured isolate derived from a Pseudomonas Aeruginosa patient sample:

https://www.ncbi.nlm.nih.gov/nucleotide/JAMOHD010000061.1

is from Henan Sputum, 2019

https://www.ncbi.nlm.nih.gov/nucleotide/JAMOHC010000055.1

Is from Henan Urine, 2019

https://www.ncbi.nlm.nih.gov/nucleotide/JAMOGJ010000101.1

Is from Henan BALF, 2019

https://www.ncbi.nlm.nih.gov/nucleotide/JAMOGH010000077.1

Is from Henan Urine, 2019.

All 4 Spike protein sequences were identical, and were found to be located within a Eukaryotic expression vector carrying the following sequences:

1: A SV40 Origin of replication, commonly used to maintain plasmids within eukaryotic cell lines through expression of the Papillomavirus/SV40 large T antigen.

2: A Neo/Kan sequence under control of the SV40 promoter, a dual bacterial/eukaryotic selectable marker that selects for transformed cells through the use of Geneticin/G418.

3: A standard CMV promoter and bgH polyA terminator for the expression of the Spike protein sequence within mammalian cells.

In addition to these changes, the furin cleavage site (PRRARS) within the Spike protein have been found to be removed, with all the 3 “R”s missing from the protein sequence leaving behind “PAS”. The “PP” sequence, which is found in both Moderna mRNA-1273 and Pfizer BNT162b2, which were used to stabilize the pre-fusion state of the Spike and were introduced very early during the design phase of these vectorized vaccines, was absent within these Spike sequences, where the native “KV” amino acids were retained. Additionally, the signal peptide sequence for the Spike protein have been replaced, and that a c-terminal protein sequence “GGGSGGGSIKEEIAKIKEEQAKIKEKIAEIEKRIAEIEKRIAGGCC” have been directly appended to the extreme c-terminus of the Spike protein. The Spike protein gene have also been subjected to recoding; however, the exact recoding scheme is distinct from either mRNA-1273 or BNT162b2.

p1

>>18183435

A BLAST analysis of this protein sequence returned no close matches other than to the Pseudomonas-hosted Spike protein itself; however, A simple sequence analysis indicate that the protein sequence contained three copies of a heptad repeat IKEE(K)I(Q)AK and two copies of a heptad repeat IEKRIAE(G), which indicate a likely conformation of a trimeric coiled coil. This comes at a surprise as the Transmembrane (TM) and C-terminal (CT) domain of Coronavirus Spike proteins are C-palmitoylated which forms a stable membrane anchor, and which neither were found to be deleted within this particular Spike protein construct. As such, this additional C-terminal protein domain would most likely function to group together multiple copies of the Spike trimer in a cluster on the cell surface, which could improve the surface expression of the Spike on the cell surface and the binding avidity of the Spike protein to molecules such as antibodies or peptides.

The presence of an intact C-terminus and an extended transmembrane anchor argue against the use of this construct for pseudotyping, as these constructs deletes the c-terminal 19AA of the Spike protein sequence as opposed to adding anything onto the C-terminus of the Spike.

This would also likely interfere with the use of such Spike protein for the purpose of creating a virus-like particle(VLP) vaccine, as a free C-terminus of the Spike is important for the interaction between the Spike, Envelope and Membrane proteins, required to form virus-like particles that are useful as vaccine antigens. The E, M or N protein sequences, which would be required for this application, were not present within PRJNA839565.

The creation of recombinant protein subunit vaccines are unlikely for this construct as vaccine antigens intended for this use are expressed as soluble proteins as opposed to being anchored to a membrane, whereas the presence of a SV40 ORI and a Neo/Kan gene intended for eukaryotic expression argues against the use of such a vector as a DNA vaccine, as these elements (persistence of expression and mammalian expression of a common Biotechnology- and Environmental- associated antigen) are undesired traits for DNA vaccines and are not intended for clinical use on patients.

While the display of large number of proteins on the surface of cells (a technique called “mammalian cell surface display”) could have been used for the purpose of screening for antibodies or other binding proteins to a specific antigen, such applications usually entail surface-displayed antibodies and fluorescence-tagged antigens that are introduced in solution, before fluorescence-activated cell sorting is used to select for cells that generated the most binding signal from the library of transformed cells.

However, the Establishment of cell surface multimeric display of Spike proteins that were resistant to TMPRSS2 and Furin (but not to cathepsins B and L or trypsin) and competent for inducing fusion under specific conditions (such as treatment with trypsin, cathepsin B or cathepsin L), does have an utility in the development of peptides that are intended for the inhibition of Coronavirus Spike-induced membrane fusion, such as the infamous EK1 peptide and its variant EK1C4. During such development process, the Spike protein are first expressed on the surface of cells, before the peptide is added and target cells are introduced. (Alternatively, a library of peptide variations could have been transformed into the target cells, with an c-terminal GPI anchor to display it on the surface of the cells) cell-to-cell fusion is activated through treatment with a specific protease, such a cathepsin L or trypsin, and after a set amount of time, the protease is either quenched by an inhibitor or removed. A split-GFP assay is then used to monitor the presence of cell-to-cell fusion, and depending on whether the peptide is added externally or displayed on the target cells, cells that were not within syncytia were selected using fluorescence-activated cell sorting and the peptide sequence from such cells were selected, subjected to further rounds of library construction and screening, until a peptide with desired capacity of inhibition of Coronavirus S-induced cell-to-cell fusion is generated.

pt2

>>18183444

This could explain the two oddities observed within the EK1 sequence: The AA site 4Q, 14Y and 32D, which were not found among the contact residues between EK1 or HR1 to the HR2 of either MERS, 229E or SARS, despite the claim that design changes made to EK1 was “on the basis of the structure of MERS-CoV S 6-HB”. When tested with different linker length and a Lipid anchor (Cholesterol), The most potent variant of EK1 that inhibited the S mediated cell-to-cell fusion of all CoV S proteins also happens to inhibit the cell-to-cell fusion activity of the SARS-CoV-2 S to the greatest extent.

Given the niche application of the observed vector format, and the fact that this is a plasmid carrying two antimicrobial resistances (AMR) genes and of which replicates within Enterobacter (which included Escherichia and Pseudomonas) and is compatible with long-term storage within cultured bacteria, It is extremely likely that this particular plasmid may have actually been within the original Bacterial isolate sample, and the most likely original application for such a plasmid would be the development of the EK1 peptide that happened to inhibit the S-mediated cell-to-cell fusion the best when anchored to the cell membrane–a condition that is most likely originally used during such a process, a method used for the high-throughput screening of such peptides from a combinatorial library.

As the cells found within the contaminated antarctic soil samples also show evidence of cell-to-cell fusion and mitochondrial DNA chimerism, a connection between these plasmid-borne, fusion-competent Spike protein sequences and the unique cell type found within these samples also can not be ruled out.

3 of 3

Vatican journalist George Neumayr who broke Cardinal McCarrick Sex Scandal dies suddenly; made a warning Tweet last month

George Neumayr

@george_neumayr

I am tangling with some dangerous forces here. Should something happen to me, close readers of my tweets will know why.

https://twitter.com/_/status/1606250063809986561

https://spectator.org/george-neumayr-rip/

https://twitter.com/0xNegEntrope/status/1616528244257292293

0xNEGEntrope

@0xNegEntrope

🚨 WEF partners with Chinese government to launch the Universal Digital Payments Network or "UDPN" 🤡Beijing-based Red Date Technologies together with US law firm DLA Piper and German IT provider GFT will launch "stablecoins" to rob, impoverish billions /1

0xNEGEntrope

@0xNegEntrope

·

4h

Replying to

@0xNegEntrope

Stablecoins came into being to compensate the victims of a major theft at HK-based Bitfinex with IOUs but quickly grew into a giant cashgrab of unbacked, "semi-backed" or "fully backed" crypto-currencies or ERC20 tokens. /2

0xNEGEntrope

@0xNegEntrope

·

4h

Naturally anything less than an fully backed and audited crypto stablecoin means literally free money for the issuer. The first stablecoin, Tether, claimed "60% backed by dollars". People sold their real money (ie fiat and Bitcoin) for these "stablecoin" dollar-like IOU notes, /3

0xNEGEntrope

@0xNegEntrope

·

4h

so that they wouldn't have to declare capital gains taxes, and thus the stablecoin had a "use-case", tax evasion. Fast-forward dozens of crypto- and finance scandals and CBDC has become the buzzword of choice for institutions and companies to scam people out of their money. /4

0xNEGEntrope

@0xNegEntrope

·

4h

Who better than Beijing to set the standards of 21st century digital financial crime? Red Date ticks every red flag box one could imagine, and claims to have invented "Blockchain-based Service Network" and "Distributed Ledger Technology".. 🤡 /5

finance.yahoo.com

Meet Red Date, the Little-Known Tech Firm Behind China’s Big Blockchain Vision

The de facto architect of China's ambitious national blockchain project reveals his game plan for making the technology cheap and easy for businesses.

0xNEGEntrope

@0xNegEntrope

·

4h

So-called "BSN", "UDPN" acronyms cleverly chosen to sound similar to existing ubiquitous tech terms (BSN an ID# for published books & UDP is a network protocol standard) would be hosted by Chinese state companies China Mobile and China Unionpay. So now we know the WEF <3 🇨🇳.. /6

0xNEGEntrope

@0xNegEntrope

·

4h

The CCP is hungry for cash; convincing people to exchange real money for monopoly money controlled by Beijing, "stablecoins" pretend to be real money but can be tracked, seized, debased/counterfeited at an insider's, or attacker's whim, further redistributing wealth from /7

0xNEGEntrope

@0xNegEntrope

·

4h

the world's poor to the CCP. This latest scam, "UDPN", wants to "bridge" stablecoin IOU-tokens with govt-backed CBDCs which do not exist yet. Basically, they want to sell you non-existent money to buy bitcoin or part-backed stablecoins, which they'll keep or exchange for cash /8

0xNEGEntrope

@0xNegEntrope

·

4h

to fill Chinese state coffers and try to make Beijing an integral part of finance, extending CCP's reach, control, censorship, intolerance and hatred further into people's everyday lives while wealth flows from your pocket straight into CCP kleptocrats' offshore accounts. /9

0xNEGEntrope

@0xNegEntrope

·

4h

Do me a favor and if u ever feel enticed to buy a stablecoin or a CBDCs, ask yourself why you're exchanging money for a higher-risk, zero profit IOU that enriches the issuer with your money while giving you zero growth prospect to even beat inflation and offloading risk to you.🤡

0xNEGEntrope

@0xNegEntrope

·

4h

China wants to run 🌎finance and replace SWIFT after Western sanctions crippled the Russian economy, and will use every opportunity lobbies like the WEF provides them to scam the world. Launching the scam at this event by a lobbying firm that says you'll own nothing is ironic. //

>>18183533

https://finance.yahoo.com/news/universal-digital-payments-network-stablecoins-110432011.html

The Universal Digital Payments Network (UDPN) was launched today at the World Economic Forumto provide interoperability between regulated stablecoins and central bank digital currencies (CBDCs).

See related article: Beyond crypto: Why would companies want cryptocurrency-free blockchains?

Fast facts

UDPN is an “advanced digital currency payments project” that “has the potential to drive down the cost of digital payments and accelerate adoption by banks and businesses of all sizes.”

The payment network was developed in the last two years by decentralized cloud infrastructure company Red Date Technology, IT solutions provider GFT, TOKO and DLA Piper.

Red Date Technology is also the developer of the Blockchain-based Service Network (BSN), the China state-backed blockchain network. The initiative has since been expanding overseas through cooperation with global enterprises on the international version of the network, BSN Spartan.

“The purpose of UDPN is to investigate a potential alternative to existing payments systems by enabling interoperability between fiat-backed tokens of stablecoins and regulated protocols,” said Marika Lulay, CEO of GFT. “The decentralized approach and geographic breadth of participating firms, combined with the advanced technological solution deployed for these trials, set this network apart.”

UDPN also enables enterprise IT systems to incorporate different digital currencies.

Multiple global banks will participate in use case proof of concepts (POCs) this month, to show how the UDPN will integrate digital currencies into daily businesses, banking and payment.

The first two POCs will involve two banks testing UDPN’s digital currency cross-border transfer and swap capabilities, and how financial institutions can execute anonymous stablecoin transfers through the “travel rule” function.

World Health Organization (WHO)

@WHO

“Vaccination is about protecting yourself, but it’s also an inherently altruistic act — you’re vaccinating yourself in order to be part of an immune group that will then protect those who can’t be vaccinated”-

@DrMikeRyan

#VaccinesWork

https://twitter.com/WHO/status/1616032454762188801

>>18183562