Experiments to Unlock How Human Bodies React to Long Space Journeys
Jan 23, 2023
Through Artemis, NASA astronauts are returning to the Moon in preparation for one day going to Mars. To better prepare astronauts for these long journeys, scientists need to know: How do extended durations in space change the human body?
Astronauts flying to the International Space Station can now volunteer for a suite of experiments that aim to help scientists learn more. Together, these experiments are called the Complement of Integrated Protocols for Human Exploration Research, or CIPHER.
“CIPHER is the first study to integrate multiple physiological and psychological measures, giving us a chance to assess the whole human response to time spent in space,” CIPHER project scientist Cherie Oubre explains. “As more astronauts head to space through Artemis and other programs, we hope to learn more about how the various systems of the body, such as the heart, muscles, bones, and eyes, adapt to long-term spaceflight.”
Through CIPHER, astronauts participate in an integrated set of 14 studies sponsored by NASA and international partner agencies. To get meaningful results, CIPHER scientists will study up to 30 astronauts, evenly divided over three mission-length categories:
Short (less than 3.5 months in space)
Standard (between 3.5 and eight months in space)
Extended (more than eight months in space)
CIPHER also includes a long-running study called Spaceflight Standard Measures, which collects a core set of information on as many crew members as possible. This core set includes metrics about the crew member’s sleep, cognition, biomarkers, immune function, microbiome, and more.
In addition to answering research questions central to each study, CIPHER takes an integrated approach – data across the CIPHER investigations will be evaluated to identify patterns and gain a deeper understanding of how the human body reacts to long durations in space. For instance: Do changes to the various systems of the body plateau across the board after specific amounts of time spent in space? Do changes in one system herald changes in another?
“CIPHER is an all-encompassing, total-body approach to learning how humans adapt to spaceflight,” says Oubre. “Insights gained through CIPHER may well be key to enabling humans to remain healthy while exploring the Moon, Mars, and beyond.”
https://www.nasa.gov/feature/experiments-to-unlock-how-human-bodies-react-to-long-space-journeys
https://www.nasa.gov/specials/artemis/
https://www.nasa.gov/hrp